Basic Science and Craniofacial Biology

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2020

Abaloparatide at the Same Dose Has the Same Effects on Bone as PTH (1-34) in Mice

Le Henaff, C., Ricarte, F., Finnie, B., He, Z., Johnson, J., Warshaw, J., Kolupaeva, V. & Partridge, N. C., Apr 1 2020, In : Journal of Bone and Mineral Research. 35, 4, p. 714-724 11 p.

Research output: Contribution to journalArticle

Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species-mediated mitochondrial injury

Castro, C. M., Corciulo, C., Solesio, M. E., Liang, F., Pavlov, E. V. & Cronstein, B. N., Apr 1 2020, In : FASEB Journal. 34, 4, p. 5027-5045 19 p.

Research output: Contribution to journalArticle

Open Access

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Angelova, P. R., Choi, M. L., Berezhnov, A. V., Horrocks, M. H., Hughes, C. D., De, S., Rodrigues, M., Yapom, R., Little, D., Dolt, K. S., Kunath, T., Devine, M. J., Gissen, P., Shchepinov, M. S., Sylantyev, S., Pavlov, E. V., Klenerman, D., Abramov, A. Y. & Gandhi, S., Jan 1 2020, (Accepted/In press) In : Cell Death and Differentiation.

Research output: Contribution to journalArticle

Open Access

Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes

Mountford, S. J., Anderson, B. M., Xu, B., Tay, E. S. V., Szabo, M., Hoang, M. L., Diao, J., Aurelio, L., Campden, R. I., Lindström, E., Sloan, E. K., Yates, R. M., Bunnett, N. W., Thompson, P. E. & Edgington-Mitchell, L. E., Mar 20 2020, In : ACS Chemical Biology. 15, 3, p. 718-727 10 p.

Research output: Contribution to journalArticle

Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents

Urso, A., D'Ovidio, F., Xu, D., Emala, C. W., Bunnett, N. W., Bunnett, N. W., Perez-Zoghbi, X. J. F. & Perez-Zoghbi, X. J. F., Feb 2020, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 2, p. L264-L275

Research output: Contribution to journalArticle

Electronic Cigarette Aerosol Modulates the Oral Microbiome and Increases Risk of Infection

Pushalkar, S., Paul, B., Li, Q., Yang, J., Vasconcelos, R., Makwana, S., González, J. M., Shah, S., Xie, C., Janal, M. N., Queiroz, E., Bederoff, M., Leinwand, J., Solarewicz, J., Xu, F., Aboseria, E., Guo, Y., Aguallo, D., Gomez, C., Kamer, A. & 7 others, Shelley, D., Aphinyanaphongs, Y., Barber, C., Gordon, T., Corby, P., Li, X. & Saxena, D., Mar 27 2020, In : iScience. 23, 3, 100884.

Research output: Contribution to journalArticle

Open Access

Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells

Aulestia, F. J., Groeling, J., Bomfim, G. H. S., Costiniti, V., Manikandan, V., Chaloemtoem, A., Concepcion, A. R., Li, Y., Wagner, L. E., Idaghdour, Y., Yule, D. I. & Lacruz, R. S., Feb 18 2020, In : Science signaling. 13, 619, eaay0086.

Research output: Contribution to journalArticle

Granulocyte-macrophage colony stimulating factor as an indirect mediator of nociceptor activation and pain

Tewari, D., Cook, A. D., Lee, M. C., Christensen, A. D., Croxford, A., Becher, B., Poole, D., Rajasekhar, P., Bunnett, N., Smith, J. E., Hamilton, J. A. & McMahon, S. B., Mar 11 2020, In : Journal of Neuroscience. 40, 10, p. 2189-2199 11 p.

Research output: Contribution to journalArticle

Inorganic polyphosphate controls cyclophilin B-mediated collagen folding in osteoblast-like cells

Khong, M. L., Li, L., Solesio, M. E., Pavlov, E. V. & Tanner, J. A., Jan 1 2020, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Inorganic polyphosphate is required for sustained free mitochondrial calcium elevation, following calcium uptake

Solesio, M. E., Garcia del Molino, L. C., Elustondo, P. A., Diao, C., Chang, J. C. & Pavlov, E. V., Mar 2020, In : Cell Calcium. 86, 102127.

Research output: Contribution to journalArticle

Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase

Esteras, N., Kundel, F., Amodeo, G. F., Pavlov, E. V., Klenerman, D. & Abramov, A. Y., Jan 1 2020, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Open Access

miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts

Malavkia, D., Shreya, S., Raj Priya, V., Rohini, M., He, Z., Partridge, N. C. & Selvamurugan, N., Jan 1 2020, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Morphological association between the muscles and bones in the craniofacial region

Yamamoto, M., Takada, H., Ishizuka, S., Kitamura, K., Jeong, J., Sato, M., Hinata, N. & Abe, S., Jan 1 2020, In : PloS one. 15, 1, e0227301.

Research output: Contribution to journalArticle

Open Access

PSGL-1 restricts HIV-1 infectivity by blocking virus particle attachment to target cells

Fu, Y., He, S., Waheed, A. A., Dabbagh, D., Zhou, Z., Trinité, B., Wang, Z., Yu, J., Wang, D., Li, F., Levy, D. N., Shang, H., Freed, E. O. & Wu, Y., Apr 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 17, p. 9537-9545 9 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Short and long period growth markers of enamel formation distinguish European Pleistocene hominins

Modesto-Mata, M., Dean, M. C., Lacruz, R. S., Bromage, T. G., García-Campos, C., Martínez de Pinillos, M., Martín-Francés, L., Martinón-Torres, M., Carbonell, E., Arsuaga, J. L. & Bermúdez de Castro, J. M., Dec 1 2020, In : Scientific reports. 10, 1, 4665.

Research output: Contribution to journalArticle

Open Access

STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone

Gamage, T. H., Lengle, E., Gunnes, G., Pullisaar, H., Holmgren, A., Reseland, J. E., Merckoll, E., Corti, S., Mizobuchi, M., Morales, R. J., Tsiokas, L., Tjønnfjord, G. E., Lacruz, R. S., Lyngstadaas, S. P., Misceo, D. & Frengen, E., Jan 2020, In : Cell Calcium. 85, 102110.

Research output: Contribution to journalArticle

Open Access

Switching of Sox9 expression during musculoskeletal system development

Nagakura, R., Yamamoto, M., Jeong, J., Hinata, N., Katori, Y., Chang, W. J. & Abe, S., Dec 1 2020, In : Scientific reports. 10, 1, 8425.

Research output: Contribution to journalArticle

Open Access

The cell-permeable mitochondrial calcium uniporter inhibitor Ru265 preserves cortical neuron respiration after lethal oxygen glucose deprivation and reduces hypoxic/ischemic brain injury

Novorolsky, R. J., Nichols, M., Kim, J. S., Pavlov, E. V., J Woods, J., Wilson, J. J. & Robertson, G. S., Jun 1 2020, In : Journal of Cerebral Blood Flow and Metabolism. 40, 6, p. 1172-1181 10 p.

Research output: Contribution to journalArticle

The Society for Craniofacial Genetics and Developmental Biology 42nd Annual Meeting

Eisenhoffer, G. T., Clouthier, D., Cox, T., Saint-Jeannet, J. P., Taneyhill, L. A., Trainor, P. A. & Moody, S. A., Jul 1 2020, In : American Journal of Medical Genetics, Part A. 182, 7, p. 1555-1561 7 p.

Research output: Contribution to journalArticle

The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability

Peng, S., Grace, M. S., Gondin, A. B., Retamal, J. S., Dill, L., Darby, W., Bunnett, N. W., Abogadie, F. C., Carbone, S. E., Tigani, T., Davis, T. P., Poole, D. P., Veldhuis, N. A. & McIntyre, P., Jan 1 2020, (Accepted/In press) In : Laboratory Investigation.

Research output: Contribution to journalArticle

TRPM7 activation potentiates SOCE in enamel cells but requires ORAI

Souza Bomfim, G. H., Costiniti, V., Li, Y., Idaghdour, Y. & Lacruz, R. S., May 2020, In : Cell Calcium. 87, 102187.

Research output: Contribution to journalArticle

Zika virus infection in chemosensory cells

Ozdener, M. H., Donadoni, M., Cicalese, S., Spielman, A. I., Garcia-Blanco, A., Gordon, J. & Sariyer, I. K., Jun 1 2020, In : Journal of neurovirology. 26, 3, p. 371-381 11 p.

Research output: Contribution to journalArticle

2019

Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity

Castro, J., Harrington, A. M., Lieu, T. M., Garcia-Caraballo, S., Maddern, J., Schober, G., O'Donnell, T., Grundy, L., Lumsden, A. L., Miller, P., Ghetti, A., Steinhoff, M. S., Poole, D. P., Dong, X., Chang, L., Bunnett, N. W. & Brierley, S. M., Oct 17 2019, In : JCI Insight. 4, 20, e131712.

Research output: Contribution to journalArticle

Open Access

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Ramírez-García, P. D., Retamal, J. S., Shenoy, P., Imlach, W., Sykes, M., Truong, N., Constandil, L., Pelissier, T., Nowell, C. J., Khor, S. Y., Layani, L. M., Lumb, C., Poole, D. P., Lieu, T. M., Stewart, G. D., Mai, Q. N., Jensen, D. D., Latorre, R., Scheff, N. N., Schmidt, B. L. & 5 others, Quinn, J. F., Whittaker, M. R., Veldhuis, N. A., Davis, T. P. & Bunnett, N. W., Dec 1 2019, In : Nature Nanotechnology. 14, 12, p. 1150-1159 10 p.

Research output: Contribution to journalArticle

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

Anderson, B. M., Poole, D. P., Aurelio, L., Ng, G. Z., Fleischmann, M., Kasperkiewicz, P., Morissette, C., Drag, M., van Driel, I. R., Schmidt, B. L., Vanner, S. J., Bunnett, N. W. & Edgington-Mitchell, L. E., Dec 1 2019, In : Scientific reports. 9, 1, 13295.

Research output: Contribution to journalArticle

Open Access

Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride

Li, Y., Liu, Y., Psoter, W. J., Nguyen, O. M., Bromage, T. G., Walters, M. A., Hu, B., Rabieh, S. & Kumararaja, F. C., Jun 1 2019, In : Caries research. 53, 4, p. 431-440 10 p.

Research output: Contribution to journalArticle

ATP Synthase C-Subunit-Deficient Mitochondria Have a Small Cyclosporine A-Sensitive Channel, but Lack the Permeability Transition Pore

Neginskaya, M. A., Solesio, M. E., Berezhnaya, E. V., Amodeo, G. F., Mnatsakanyan, N., Jonas, E. A. & Pavlov, E. V., Jan 2 2019, In : Cell Reports. 26, 1, p. 11-17.e2

Research output: Contribution to journalArticle

Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model

Wang, S., Wang, N., Yu, B., Cao, M., Wang, Y., Guo, Y., Zhang, Y., Zhang, P., Yu, X., Wang, S., Zeng, L., Liang, B., Li, X. & Wu, Y., Sep 5 2019, In : Oncogene. 38, 36, p. 6338-6353 16 p.

Research output: Contribution to journalArticle

Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody

He, S., Fu, Y., Guo, J., Spear, M., Yang, J., Trinité, B., Qin, C., Fu, S., Jiang, Y., Zhang, Z., Xu, J., Ding, H., Levy, D. N., Chen, W., Petricoin, E., Liotta, L. A., Shang, H. & Wu, Y., Jan 1 2019, In : Virginia Law Review. 104, 8, eaat7911.

Research output: Contribution to journalArticle

Comparative Effect of Two Red Lights on Streptococcus mutans Biofilms and Assessment of Temperature Variances in Human Teeth During In Vitro Photodynamic Antimicrobial Chemotherapy

Aragão, M. G. B., Costa, C. A. G. D. A., Lima, R. A., Rodrigues, L. K. A., Duarte, S. & Zanin, I. C. J., Jan 2019, In : Photobiomodulation, photomedicine, and laser surgery. 37, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Open Access

Daily phototherapy with red light to regulate candida albicans biofilm growth

Panariello, B. H. D., Garcia, B. A. & Duarte, S., Apr 2019, In : Journal of Visualized Experiments. 2019, 146, e59326.

Research output: Contribution to journalArticle

Differential regulation of Ca2+ influx by Orai channels mediates enamel mineralization

Eckstein, M., Vaeth, M., Aulestia, F. J., Costiniti, V., Kassam, S. N., Bromage, T. G., Pedersen, P., Issekutz, T., Idaghdour, Y., Moursi, A. M., Feske, S. & Lacruz, R. S., Jan 1 2019, In : Science signaling. 12, 578, aav4663.

Research output: Contribution to journalArticle

Dual role of inorganic polyphosphate in cardiac myocytes: The importance of polyP chain length for energy metabolism and mPTP activation

Seidlmayer, L. K., Gomez-Garcia, M. R., Shiba, T., Porter, G. A., Pavlov, E. V., Bers, D. M. & Dedkova, E. N., Feb 15 2019, In : Archives of Biochemistry and Biophysics. 662, p. 177-189 13 p.

Research output: Contribution to journalArticle

Open Access

Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression

Israelyan, N., Del Colle, A., Li, Z., Park, Y., Xing, A., Jacobsen, J. P. R., Luna, R. A., Jensen, D. D., Madra, M., Saurman, V., Rahim, R., Latorre, R., Law, K., Carson, W., Bunnett, N. W., Caron, M. G. & Margolis, K. G., Aug 2019, In : Gastroenterology. 157, 2, p. 507-521.e4

Research output: Contribution to journalArticle

Effects of the Tobacco Carcinogens N′-Nitrosonornicotine and Dibenzo[ a, l]pyrene Individually and in Combination on DNA Damage in Human Oral Leukoplakia and on Mutagenicity and Mutation Profiles in lacI Mouse Tongue

Guttenplan, J. B., Chen, K. M., Sun, Y. W., Shalaby, N. A. E., Kosinska, W., Desai, D., Gowda, K., Amin, S. & El-Bayoumy, K., Sep 16 2019, In : Chemical research in toxicology. 32, 9, p. 1893-1899 7 p.

Research output: Contribution to journalArticle

Identification of ZYG11A as a candidate IGF1-dependent protooncogene in endometrial cancer

Achlaug, L., Sarfstein, R., Nagaraj, K., Lapkina-Gendler, L., Bruchim, I., Dixit, M., Laron, Z., Yakar, S. & Werner, H., Jul 1 2019, In : Oncotarget. 10, 43, p. 4437-4448 12 p.

Research output: Contribution to journalArticle

Inhibition of Karyopherin beta 1 suppresses prostate cancer growth

Yang, J., Guo, Y., Lu, C., Zhang, R., Wang, Y., Luo, L., Zhang, Y., Chu, C. H., Wang, K. J., Obbad, S., Yan, W. & Li, X., Jun 13 2019, In : Oncogene. 38, 24, p. 4700-4714 15 p.

Research output: Contribution to journalArticle

Innate αβ T cells mediate antitumor immunity by orchestrating immunogenic macrophage programming

Hundeyin, M., Kurz, E., Mishra, A., Rossi, J. A. K., Liudahl, S. M., Leis, K. R., Mehrotra, H., Kim, M., Torres, L. E., Ogunsakin, A., Link, J., Sears, R. C., Sivagnanam, S., Goecks, J., Islam, K. M. S., Dolgalev, I., Savadkar, S., Wang, W., Aykut, B., Leinwand, J. & 17 others, Diskin, B., Adam, S., Israr, M., Gelas, M., Lish, J., Chin, K., Farooq, M. S., Wadowski, B., Wu, J., Shah, S., Adeegbe, D. O., Pushalkar, S., Vasudevaraja, V., Saxena, D., Wong, K. K., Coussens, L. M. & Miller, G., Jan 1 2019, In : Cancer Discovery. 9, 9, p. 1288-1305 18 p.

Research output: Contribution to journalArticle

Open Access

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

Ran, L., Wang, X., Mi, A., Liu, Y., Wu, J., Wang, H., Guo, M., Sun, J., Liu, B., Li, Y., Wang, D., Jiang, R., Wang, N., Gao, W., Zeng, L., Huang, L., Chen, X., LeRoith, D., Liang, B., Li, X. & 1 others, Wu, Y., Jun 28 2019, In : iScience. 16, p. 106-121 16 p.

Research output: Contribution to journalArticle

Open Access

Low IGF-I bioavailability impairs growth and glucose metabolism in a mouse model of human PAPPA2 p.ALA1033Val mutation

Fujimoto, M., Andrew, M., Liao, L., Zhang, D., Yildirim, G., Sluss, P., Kalra, B., Kumar, A., Yakar, S., Hwa, V. & Dauber, A., Jun 1 2019, In : Endocrinology. 160, 6, p. 1363-1376 14 p.

Research output: Contribution to journalArticle

Low-temperature plasma on peri-implant–related biofilm and gingival tissue

Carreiro, A. F. P., Delben, J. A., Guedes, S., Silveira, E. J. D., Janal, M. N., Vergani, C. E., Pushalkar, S. & Duarte, S., Jan 1 2019, In : Journal of periodontology. 90, 5, p. 507-515 9 p.

Research output: Contribution to journalArticle

Mammalian Taste Cells Express Functional Olfactory Receptors

Malik, B., Elkaddi, N., Turkistani, J., Spielman, A. I. & Ozdener, M. H., Jun 2019, In : Chemical senses. 44, 5, p. 289-301 13 p., bjz019.

Research output: Contribution to journalArticle

Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long-Lived Growth Hormone Receptor Null Mice

Liu, Z., Solesio, M. E., Schaffler, M. B., Frikha-Benayed, D., Rosen, C. J., Werner, H., Kopchick, J. J., Pavlov, E. V., Abramov, A. Y. & Yakar, S., Jan 2019, In : Journal of Bone and Mineral Research. 34, 1, p. 106-122 17 p.

Research output: Contribution to journalArticle

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

Dasgupta, K., Chung, J. U., Asam, K. & Jeong, J., Nov 15 2019, In : Developmental Biology. 455, 2, p. 434-448 15 p.

Research output: Contribution to journalArticle

NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal

Trinité, B., Zhang, H. & Levy, D. N., Jun 26 2019, In : Retrovirology. 16, 1, 17.

Research output: Contribution to journalArticle

Open Access

Non-thermal plasma treatment to enhance the adhesion between enamel surface and orthodontic bracket

Almoammar, S., Alshahrani, I., Asiry, M. A., Duarte, S., Janal, M. & Khoo, E., Jan 1 2019, In : Bio-Medical Materials and Engineering. 30, 4, p. 439-448 10 p.

Research output: Contribution to journalArticle

Parathyroid hormone-stimulation of Runx2 during osteoblast differentiation via the regulation of lnc-SUPT3H-1:16 (RUNX2-AS1:32) and miR-6797-5p

Arumugam, B., Vishal, M., Shreya, S., Malavika, D., Rajpriya, V., He, Z., Partridge, N. C. & Selvamurugan, N., Mar 2019, In : Biochimie. 158, p. 43-52 10 p.

Research output: Contribution to journalArticle

Periodontal disease in a young Romanian convenience sample: Radiographic assessment

Hategan, S. I., Kamer, A. R., Sinescu, C., Craig, R. G., Jivanescu, A., Gavrilovici, A. M. & Negrutiu, M. L., May 29 2019, In : BMC Oral Health. 19, 1, 94.

Research output: Contribution to journalArticle

Open Access