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David Fitch

Professor Of Biology

    1980 …2019

    Research output per year

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    Research Output

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    2019

    The Long Non-Coding RNA lep-5 Promotes the Juvenile-to-Adult Transition by Destabilizing LIN-28

    Kiontke, K. C., Herrera, R. A., Vuong, E., Luo, J., Schwarz, E. M., Fitch, D. H. A. & Portman, D. S., May 20 2019, In : Developmental Cell. 49, 4, p. 542-555.e9

    Research output: Contribution to journalArticle

    The makorin lep-2 and the lncrna lep-5 regulate lin-28 to schedule sexual maturation of the c. Elegans nervous system

    Lawson, H., Vuong, E., Miller, R. M., Kiontke, K., Fitch, D. H. & Portman, D. S., Jan 1 2019, In : eLife. 8, e43660.

    Research output: Contribution to journalArticle

    Open Access
    2018

    From “the worm” to “the worms” and back again: The evolutionary developmental biology of nematodes

    Haag, E. S., Fitch, D. H. A. & Delattre, M., Oct 2018, In : Genetics. 210, 2, p. 397-433 37 p.

    Research output: Contribution to journalArticle

    2017

    Genome Architecture and Evolution of a Unichromosomal Asexual Nematode

    Fradin, H., Kiontke, K., Zegar, C., Gutwein, M., Lucas, J., Kovtun, M., Corcoran, D. L., Baugh, L. R., Fitch, D. H. A., Piano, F. & Gunsalus, K. C., Oct 9 2017, In : Current Biology. 27, 19, p. 2928-2939.e6

    Research output: Contribution to journalArticle

    2016

    Makorin ortholog LEP-2 regulates LIN-28 stability to promote the juvenile-to-adult transition in Caenorhabditis elegans

    Antonio Herrera, R., Kiontke, K. & Fitch, D. H. A., Mar 1 2016, In : Development (Cambridge). 143, 5, p. 799-809 11 p.

    Research output: Contribution to journalArticle

    2014

    A critique of Rossberg et al. Noise obscures the genetic signal of meiobiotal ecospecies in ecogenomic datasets

    Morgan, M. J., Bass, D., Bik, H., Birky, C. W., Blaxter, M., Crisp, M. D., Derycke, S., Fitch, D., Fontaneto, D., Hardy, C. M., King, A. J., Kiontke, K. C., Moens, T., Pawlowski, J. W., Porazinska, D., Tang, C. Q., Thomas, W. K., Yeates, D. K. & Creer, S., Mar 26 2014, In : Proceedings of the Royal Society B: Biological Sciences. 281, 1783, 20133076.

    Research output: Contribution to journalArticle

    Comparative validation of the D. melanogaster modENCODE transcriptome annotation

    Chen, Z. X., Sturgill, D., Qu, J., Jiang, H., Park, S., Boley, N., Suzuki, A. M., Fletcher, A. R., Plachetzki, D. C., FitzGerald, P. C., Artieri, C. G., Atallah, J., Barmina, O., Brown, J. B., Blankenburg, K. P., Clough, E., Dasgupta, A., Gubbala, S., Han, Y., Jayaseelan, J. C. & 43 others, Kalra, D., Kim, Y. A., Kovar, C. L., Lee, S. L., Li, M., Malley, J. D., Malone, J. H., Mathew, T., Mattiuzzo, N. R., Munidasa, M., Muzny, D. M., Ongeri, F., Perales, L., Przytycka, T. M., Pu, L. L., Robinson, G., Thornton, R. L., Saada, N., Scherer, S. E., Smith, H. E., Vinson, C., Warner, C. B., Worley, K. C., Wu, Y. Q., Zou, X., Cherbas, P., Kellis, M., Eisen, M. B., Piano, F., Kionte, K., Fitch, D. H., Sternberg, P. W., Cutter, A. D., Duff, M. O., Hoskins, R. A., Graveley, B. R., Gibbs, R. A., Bickel, P. J., Kopp, A., Carninci, P., Celniker, S. E., Oliver, B. & Richards, S., Jul 2014, In : Genome Research. 24, 7, p. 1209-1223 15 p.

    Research output: Contribution to journalArticle

    2011

    A bow-tie genetic architecture for morphogenesis suggested by a genome-wide RNAi screen in Caenorhabditis elegans

    Nelson, M. D., Zhou, E., Kiontke, K., Fradin, H., Maldonado, G., Martin, D., Shah, K. & Fitch, D. H. A., Mar 1 2011, In : PLoS genetics. 7, 3, e1002010.

    Research output: Contribution to journalArticle

    A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits

    Kiontke, K. C., Félix, M. A., Ailion, M., Rockman, M. V., Braendle, C., Pénigault, J. B. & Fitch, D. H. A., Nov 22 2011, In : BMC Evolutionary Biology. 11, 1, 339.

    Research output: Contribution to journalArticle

    Overlap extension PCR: an efficient method for transgene construction.

    Nelson, M. D. & Fitch, D. H. A., 2011, In : Methods in molecular biology (Clifton, N.J.). 772, p. 459-470 12 p.

    Research output: Contribution to journalArticle

    2009

    Evolution of early embryogenesis in rhabditid nematodes

    Brauchle, M., Kiontke, K., MacMenamin, P., Fitch, D. H. A. & Piano, F., Nov 1 2009, In : Developmental Biology. 335, 1, p. 253-262 10 p.

    Research output: Contribution to journalArticle

    2008

    Teratorhabditis synpapillata Sudhaus, 1985 (Rhabditida: Rhabditidae) is an associate of the red palm weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae)

    Kanzaki, N., Abe, F., Giblin-Davis, R. M., Kiontke, K., Fitch, D. H. A., Hata, K. & Soné, K., Jan 3 2008, In : Nematology. 10, 2, p. 207-218 12 p.

    Research output: Contribution to journalArticle

    2007

    Population structure of plasmid-containing strains of Streptococcus mutans, a member of the human indigenous biota

    Caufield, P. W., Saxena, D., Fitch, D. & Li, Y., Feb 1 2007, In : Journal of bacteriology. 189, 4, p. 1238-1243 6 p.

    Research output: Contribution to journalArticle

    Trends, Stasis, and Drift in the Evolution of Nematode Vulva Development

    Kiontke, K., Barrière, A., Kolotuev, I., Podbilewicz, B., Sommer, R., Fitch, D. H. A. & Félix, M. A., Nov 20 2007, In : Current Biology. 17, 22, p. 1925-1937 13 p.

    Research output: Contribution to journalArticle

    2006

    Novel gain-of-function alleles demonstrate a role for the heterochronic gene lin-41 in C. elegans male tail tip morphogenesis

    Del Rio-Albrechtsen, T., Kiontke, K., Chiou, S. Y. & Fitch, D. H. A., Sep 1 2006, In : Developmental Biology. 297, 1, p. 74-86 13 p.

    Research output: Contribution to journalArticle

    2005

    Autosomal genes of autosomal/X-linked duplicated gene pairs and germ-line proliferation in Caenorhabditis elegans

    Maciejowski, J., Ahn, J. H., Cipriani, P. G., Killian, D. J., Chaudhary, A. L., Ji, I. L., Voutev, R., Johnsen, R. C., Baillie, D. L., Gunsalus, K. C., Fitch, D. H. A. & Hubbard, E. J. A., Apr 1 2005, In : Genetics. 169, 4, p. 1997-2011 15 p.

    Research output: Contribution to journalArticle

    2004

    Caenorhabditis phylogeny predicts convergence of hermaphroditism and extensive intron loss

    Kiontke, K., Gavin, N. P., Raynes, Y., Roehrig, C., Piano, F. & Fitcht, D. H. A., Jun 15 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 24, p. 9003-9008 6 p.

    Research output: Contribution to journalArticle

    2003

    Absence of Wolbachia in Nonfilariid Nematodes

    Bordenstein, S. R., Fitch, D. H. A. & Werren, J. H., Sep 1 2003, In : Journal of Nematology. 35, 3, p. 266-270 5 p.

    Research output: Contribution to journalArticle

    The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics

    Stein, L. D., Bao, Z., Blasiar, D., Blumenthal, T., Brent, M. R., Chen, N., Chinwalla, A., Clarke, L., Clee, C., Coghlan, A., Coulson, A., D'Eustachio, P., Fitch, D. H. A., Fulton, L. A., Fulton, R. E., Griffiths-Jones, S., Harris, T. W., Hillier, L. W., Kamath, R., Kuwabara, P. E. & 16 others, Mardis, E. R., Marra, M. A., Miner, T. L., Minx, P., Mullikin, J. C., Plumb, R. W., Rogers, J., Schein, J. E., Sohrmann, M., Spieth, J., Stajich, J. E., Wei, C., Willey, D., Wilson, R. K., Durbin, R. & Waterston, R. H., Dec 1 2003, In : PLoS biology. 1, 2

    Research output: Contribution to journalArticle

    2002

    TLP-1 is an asymmetric cell fate determinant that responds to Wnt signals and controls male tail tip morphogenesis in C. elegans

    Zhao, X., Yang, Y., Fitch, D. H. A. & Herman, M. A., Aug 23 2002, In : Development. 129, 6, p. 1497-1508 12 p.

    Research output: Contribution to journalArticle

    2001

    Comparative studies on the phylogeny and systematics of the Rhabditidae (Nematoda)

    Sudhaus, W. & Fitch, D., Mar 1 2001, In : Journal of Nematology. 33, 1, p. 1-70 70 p.

    Research output: Contribution to journalArticle

    2000

    Evolution of "Rhabditidae" and the male tail

    Fitch, D. H. A., Sep 1 2000, In : Journal of Nematology. 32, 3, p. 235-244 10 p.

    Research output: Contribution to journalArticle

    Rearrangement of immunoglobulin genes in shark germ cells

    Lee, S. S., Fitch, D., Flajnik, M. F. & Hsu, E., May 15 2000, In : Journal of Experimental Medicine. 191, 10, p. 1637-1647 11 p.

    Research output: Contribution to journalArticle

    1999

    Morphogenesis of the Caenorhabditis elegans male tail tip

    Nguyen, C. Q., Hall, D. H., Yang, Y. & Fitch, D. H. A., Mar 1 1999, In : Developmental Biology. 207, 1, p. 86-106 21 p.

    Research output: Contribution to journalArticle

    1997

    Evolution of male tail development in rhabditid nematodes related to Caenorhabditis elegans

    Fitch, D. H. A., Mar 1997, In : Systematic Biology. 46, 1, p. 145-179 35 p.

    Research output: Contribution to journalArticle

    1995

    18S ribosomal RNA gene phylogeny for some rhabditidae related to Caenorhabditis

    Fitch, D. H. A., Bugaj-Gaweda, B. & Emmons, S. W., Jan 1 1995, In : Molecular Biology and Evolution. 12, 2, p. 346-358 13 p.

    Research output: Contribution to journalArticle

    1994

    Caenorhabditis vulgaris sp.n. (Nematoda: Rhabditidae): A necromenic associate of pill bugs and snails

    Baird, S. E., Fitch, D. H. A. & Emmons, S. W., Dec 1 1994, In : Nematologica. 40, 1-4, p. 1-11 11 p.

    Research output: Contribution to journalArticle

    Widespread occurrence of the Tc1 transposon family: Tc1-like transposons from teleost fish

    Radice, A. D., Bugaj, B., Fitch, D. H. A. & Emmons, S. W., Nov 1 1994, In : MGG Molecular & General Genetics. 244, 6, p. 606-612 7 p.

    Research output: Contribution to journalArticle

    1993

    Low codon bias and high rates of synonymous substitution in Drosophila hydei and D. melanogaster histone genes

    Fitch, D. H. A. & Strausbaugh, L. D., Jan 1 1993, In : Molecular Biology and Evolution. 10, 2, p. 397-413 17 p.

    Research output: Contribution to journalArticle

    1992
    1991

    Duplication of the γ-globin gene mediated by L1 long interspersed repetitive elements in an early ancestor of simian primates

    Fitch, D. H. A., Bailey, W. J., Tagle, D. A., Goodman, M., Sieu, L. & Slightom, J. L., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 16, p. 7396-7400 5 p.

    Research output: Contribution to journalArticle

    Open Access

    Molecular evolution of the Ψη-globin gene locus: Gibbon phylogeny and the hominoid slowdown

    Bailey, W. J., Fitch, D. H. A., Tagle, D. A., Czelusniak, J., Slightom, J. L. & Goodman, M., Mar 6 1991, In : Molecular Biology and Evolution. 8, 2, p. 155-184 30 p.

    Research output: Contribution to journalArticle

    Pattern formation in the nematode epidermis: Determination of the arrangement of peripheral sense organs in the C. elegans male tail

    Baird, S. E., Fitch, D. H. A., Kassem, I. A. A. & Emmons, S. W., Nov 18 1991, In : Development. 113, 2, p. 515-526 12 p.

    Research output: Contribution to journalArticle

    Phylogenetic scanning: A computer-assisted algorithm for mapping gene conversions and other recombinational events

    Fitch, D. H. A. & Goodman, M., Apr 1 1991, In : Bioinformatics. 7, 2, p. 207-215 9 p.

    Research output: Contribution to journalArticle

    1990

    Molecular history of gene conversions in the primate fetal γ-globin genes. Nucleotide sequences from the common gibbon, Hylobates lar

    Fitch, D. H. A., Mainone, C., Goodman, M. & Slightom, J. L., Feb 12 1990, In : Journal of Biological Chemistry. 265, 2, p. 781-793 13 p.

    Research output: Contribution to journalArticle

    On the origins of tandemly repeated genes: Does histone gene copy number in Drosophila reflect chromosomal location?

    Fitch, D. H. A., Strausbaugh, L. D. & Barrett, V., Apr 1 1990, In : Chromosoma. 99, 2, p. 118-124 7 p.

    Research output: Contribution to journalArticle

    Primate evolution at the DNA level and a classification of hominoids

    Goodman, M., Tagle, D. A., Fitch, D. H. A., Bailey, W., Czelusniak, J., Koop, B. F., Benson, P. & Slightom, J. L., Mar 1 1990, In : Journal of Molecular Evolution. 30, 3, p. 260-266 7 p.

    Research output: Contribution to journalArticle

    1988

    The spider monkey ψη-globin gene and surrounding sequences: Recent or ancient insertions of LINEs and SINEs?

    Fitch, D. H. A., Mainone, C., Sligtom, J. L. & Goodman, M., Oct 1988, In : Genomics. 3, 3, p. 237-255 19 p.

    Research output: Contribution to journalArticle

    1980

    External review in quality assurance

    Darnell, R. E. & Fitch, D. H., 1980, In : Physical Therapy. 60, 5, p. 559-63

    Research output: Contribution to journalArticle