No photo of David Scicchitano

David Scicchitano

Professor of Biology

    1982 …2018

    Research output per year

    If you made any changes in Pure these will be visible here soon.

    Research Output

    Filter
    Article
    2018

    Genetic instability associated with loop or stem-loop structures within transcription units can be independent of nucleotide excision repair

    Burns, J. A., Chowdhury, M. A., Cartularo, L., Berens, C. & Scicchitano, D. A., Apr 20 2018, In : Nucleic acids research. 46, 7, p. 3498-3516 19 p.

    Research output: Contribution to journalArticle

    Open Access

    O6-methylguanine–induced transcriptional mutagenesis reduces p53 tumor-suppressor function

    Ezerskyte, M., Paredes, J. A., Malvezzi, S., Burns, J. A., Margison, G. P., Olsson, M., Scicchitano, D. A. & Dreij, K., May 1 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. 4731-4736 6 p.

    Research output: Contribution to journalArticle

    2017

    The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RNA Polymerase II Elongation in Vitro

    Kolbanovskiy, M., Chowdhury, M. A., Nadkarni, A., Broyde, S., Geacintov, N. E., Scicchitano, D. A. & Shafirovich, V., Jun 20 2017, In : Biochemistry. 56, 24, p. 3008-3018 11 p.

    Research output: Contribution to journalArticle

    2016

    Nucleotide excision repair and transcription-coupled DNA repair abrogate the impact of DNA damage on transcription

    Nadkarni, A., Burns, J. A., Gandolfi, A., Chowdhury, M. A., Cartularo, L., Berens, C., Geacintov, N. E. & Scicchitano, D. A., Jan 8 2016, In : Journal of Biological Chemistry. 291, 2, p. 848-861 14 p.

    Research output: Contribution to journalArticle

    2010

    O6-Methylguanine induces altered proteins at the level of transcription in human cells

    Burns, J. A., Dreij, K., Cartularo, L. & Scicchitano, D. A., Dec 2010, In : Nucleic acids research. 38, 22, p. 8178-8187 10 p.

    Research output: Contribution to journalArticle

    2008

    Transcription elongation past O6-methylguanine by human RNA polymerase II and bacteriophage T7 RNA polymerase

    Dimitri, A., Burns, J. A., Broyde, S. & Scicchitano, D. A., 2008, In : Nucleic acids research. 36, 20, p. 6459-6471 13 p.

    Research output: Contribution to journalArticle

    Transcription of DNA containing the 5-guanidino-4-nitroimidazole lesion by human RNA polymerase II and bacteriophage T7 RNA polymerase

    Dimitri, A., Jia, L., Shafirovich, V., Geacintov, N. E., Broyde, S. & Scicchitano, D. A., Aug 2 2008, In : DNA Repair. 7, 8, p. 1276-1288 13 p.

    Research output: Contribution to journalArticle

    Transcription Processing at 1,N2-Ethenoguanine by Human RNA Polymerase II and Bacteriophage T7 RNA Polymerase

    Dimitri, A., Goodenough, A. K., Guengerich, F. P., Broyde, S. & Scicchitano, D. A., Jan 11 2008, In : Journal of Molecular Biology. 375, 2, p. 353-366 14 p.

    Research output: Contribution to journalArticle

    2007
    2004
    2003

    Construction and purification of site-specifically modified DNA templates for transcription assays.

    Perlow, R. A., Schinecker, T. M., Kim, S. J., Geacintov, N. E. & Scicchitano, D. A., Apr 1 2003, In : Nucleic acids research. 31, 7, p. e40

    Research output: Contribution to journalArticle

    Open Access
    2002

    Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes

    Plosky, B., Samson, L., Engelward, B. P., Gold, B., Schlaen, B., Millas, T., Magnotti, M., Schor, J. & Scicchitano, D. A., Aug 6 2002, In : DNA Repair. 1, 8, p. 683-696 14 p.

    Research output: Contribution to journalArticle

    2001
    1997
    Open Access
    1995
    1994

    Site-Specific Benzo[a]pyrene Diol Epoxide-DNA Adducts Inhibit Transcription Elongation by Bacteriophage T7 RNA Polymerase

    Choi, D. J., Marino-Alessandri, D. J., Geacintov, N. E. & Scicchitano, D. A., Jan 1 1994, In : Biochemistry. 33, 3, p. 780-787 8 p.

    Research output: Contribution to journalArticle

    1992

    Intragenomic repair heterogeneity of DNA damage

    Scicchitano, D. A. & Hanawalt, P. C., 1992, In : Environmental health perspectives. 98, p. 45-51 7 p.

    Research output: Contribution to journalArticle

    1991

    Two expressed human genes sustain slightly more DNA damage after alkylating agent treatment than an inactive gene

    Bartlett, J. D., Scicchitano, D. A. & Robison, S. H., Nov 1991, In : Mutation Research-DNA Repair. 255, 3, p. 247-256 10 p.

    Research output: Contribution to journalArticle

    1990

    Lack of sequence-specific removal of N-methylpurines from cellular DNA

    Scicchitano, D. A. & Hanawalt, P. C., 1990, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 233, 1-2, p. 31-37 7 p.

    Research output: Contribution to journalArticle

    Measurements of genomic and gene-specific DNA repair of alkylation damage in cultured human T-lymphocytes.

    Hartshorn, J. N., Scicchitano, D. A. & Robison, S. H., 1990, In : Basic life sciences. 53, p. 233-249 17 p.

    Research output: Contribution to journalArticle

    1989
    Open Access
    1988

    Use of oligodeoxynucleotides containing o6-alkylguanine for the assay of o6-alkylguanine-dna-alkyl transferase activity

    Dolan, M. E., Schicchitiano, D. & Pegg, A. E., Mar 1988, In : Cancer Research. 48, 5, p. 1184-1188 5 p.

    Research output: Contribution to journalArticle

    1987

    Inhibition of O6-alkylguanine-DNA-alkyltransferase by metals

    Scicchitano, D. A. & Pegg, A. E., Nov 1987, In : Mutation Research Letters. 192, 3, p. 207-210 4 p.

    Research output: Contribution to journalArticle

    Specificity of O6-alkylguanine-DNA alkyltransferase.

    Pegg, A. E., Scicchitano, D., Morimoto, K. & Dolan, M. E., 1987, In : IARC scientific publications. 84, p. 30-34 5 p.

    Research output: Contribution to journalArticle

    1986

    Repair of oligodeoxynucleotides containing o-methylguanine by o-alkylguanine-dna-alkyltransferase

    Scicchitano, D., Jones, R. A., Kuzmich, S., Gaffney, B., Lasko, D. D., Essigmann, J. M. & Pegg, A. E., 1986, In : Carcinogenesis. 7, 8, p. 1383-1386 4 p.

    Research output: Contribution to journalArticle

    1985

    Repair of o-propylguanine and o-butylguanine in dna by o-alkylguanine-dna alkyltransferases from rat liver and E. coli

    Morimoto, K., Dolan, M. E., Scicchitano, D. & Pegg, A. E., Jul 1985, In : Carcinogenesis. 6, 7, p. 1027-1031 5 p.

    Research output: Contribution to journalArticle

    Studies of the repair of O6-alkylguanine and O4-alkylthymine in DNA by alkyltransferases from mammalian cells and bacteria

    Pegg, A. E., Dolan, M. E., Scicchitano, D. & Morimoto, K., 1985, In : Environmental health perspectives. VOL. 62, p. 109-114 6 p.

    Research output: Contribution to journalArticle

    Open Access
    1984

    Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli

    Dolan, M. E., Scicchitano, D., Singer, B. & Pegg, A. E., Aug 30 1984, In : Biochemical and Biophysical Research Communications. 123, 1, p. 324-330 7 p.

    Research output: Contribution to journalArticle

    Comparison of the Rates off Repair off O6-Alkylguanines in DNA by Rat Liver and Bacterial O6-Alkylguanine-DNA Alkyltransferase

    Pegg, A. E., Scicchitano, D. & Dolan, M. E., Sep 1 1984, In : Cancer Research. 44, 9, p. 3806-3811 6 p.

    Research output: Contribution to journalArticle

    1982