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Elodie Ghedin

Professor of Biology and Public Health

    1993 …2020

    Research output per year

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    Research Output

    2015

    Identification and analysis of ingi-related retroposons in the trypanosomatid genomes

    Bringaud, F., Rogers, M. & Ghedin, E., 2015, In : Methods in Molecular Biology. 1201, p. 109-122 14 p.

    Research output: Contribution to journalArticle

    Identification of mammalian-adapting mutations in the polymerase complex of an avian H5N1 influenza virus

    Taft, A. S., Ozawa, M., Fitch, A., Depasse, J. V., Halfmann, P. J., Hill-Batorski, L., Hatta, M., Friedrich, T. C., Lopes, T. J. S., Maher, E. A., Ghedin, E., Macken, C. A., Neumann, G. & Kawaoka, Y., Jun 17 2015, In : Nature communications. 6, 7491.

    Research output: Contribution to journalArticle

    Intrahost dynamics of antiviral resistance in influenza a virus reflect complex patterns of segment linkage, reassortment, and natural selection

    Rogers, M. B., Song, T., Sebra, R., Greenbaum, B. D., Hamelin, M. E., Fitch, A., Twaddle, A., Cui, L., Holmes, E. C., Boivin, G. & Ghedina, E., Apr 7 2015, In : mBio. 6, 2, e02464-14.

    Research output: Contribution to journalArticle

    Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals

    Beck, J. M., Schloss, P. D., Venkataraman, A., Twigg H., ., Jablonski, K. A., Bushman, F. D., Campbell, T. B., Charlson, E. S., Collman, R. G., Crothers, K., Curtis, J. L., Drews, K. L., Flores, S. C., Fontenot, A. P., Foulkes, M. A., Frank, I., Ghedin, E., Huang, L., Lynch, S. V., Morris, A. & 5 others, Palmer, B. E., Schmidt, T. M., Sodergren, E., Weinstock, G. M. & Young, V. B., 2015, In : American Journal of Respiratory and Critical Care Medicine. 192, 11, p. 1335-44

    Research output: Contribution to journalArticle

    Myxoma virus and the leporipoxviruses: An evolutionary paradigm

    Kerr, P. J., Liu, J., Cattadori, I., Ghedin, E., Read, A. F. & Holmes, E. C., 2015, In : Viruses. 7, 3, p. 1020-1061 42 p.

    Research output: Contribution to journalReview article

    The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles

    Tarabichi, Y., Li, K., Hu, S., Nguyen, C., Wang, X., Elashoff, D., Saira, K., Frank, B., Bihan, M., Ghedin, E., Methé, B. A. & Deng, J. C., Dec 15 2015, In : Microbiome. 3, 1 p.

    Research output: Contribution to journalArticle

    Topographic diversity of the respiratory tract mycobiome and alteration in HIV and lung disease

    Cui, L., Lucht, L., Tipton, L., Rogers, M. B., Fitch, A., Kessinger, C., Camp, D., Kingsley, L., Leo, N., Greenblatt, R. M., Fong, S., Stone, S., Dermand, J. C., Kleerup, E. C., Huang, L., Morris, A. & Ghedin, E., Apr 15 2015, In : American Journal of Respiratory and Critical Care Medicine. 191, 8, p. 932-942 11 p.

    Research output: Contribution to journalArticle

    Viral evolution: Beyond drift and shift

    Greenbaum, B. D. & Ghedin, E., Aug 1 2015, In : Current Opinion in Microbiology. 26, p. 109-115 7 p.

    Research output: Contribution to journalReview article

    2014

    A large-scale immuno-epidemiological simulation of influenza A epidemics

    Lukens, S., Depasse, J., Rosenfeld, R., Ghedin, E., Mochan, E., Brown, S. T., Grefenstette, J., Burke, D. S., Swigon, D. & Clermont, G., Sep 29 2014, In : BMC public health. 14, 1, 1019.

    Research output: Contribution to journalArticle

    Arboretum and Puerto Almendras viruses: Two novel rhabdoviruses isolated from mosquitoes in Peru

    Vasilakis, N., Castro-Llanos, F., Widen, S. G., Aguilar, P. V., Guzman, H., Guevara, C., Fernandez, R., Auguste, A. J., Wood, T. G., Popov, V., Mundal, K., Ghedin, E., Kochel, T. J., Holmes, E. C., Walker, P. J. & Tesh, R. B., 2014, In : Journal of General Virology. 95, PART 4, p. 787-792 6 p.

    Research output: Contribution to journalArticle

    Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design

    Gardner, C. L., Hritz, J., Sun, C., Vanlandingham, D. L., Song, T. Y., Ghedin, E., Higgs, S., Klimstra, W. B. & Ryman, K. D., Feb 2014, In : PLoS neglected tropical diseases. 8, 2, e2719.

    Research output: Contribution to journalArticle

    Emerging and resistant infections

    Clancy, C. J., Kalil, A. C., Fowler, V. G., Ghedin, E., Kolls, J. K. & Nguyen, M. H., Aug 1 2014, In : Annals of the American Thoracic Society. 11, p. S193-S200

    Research output: Contribution to journalArticle

    Mesoniviruses are mosquito-specific viruses with extensive geographic distribution and host range

    Vasilakis, N., Guzman, H., Firth, C., Forrester, N. L., Widen, S. G., Wood, T. G., Rossi, S. L., Ghedin, E., Popov, V., Blasdell, K. R., Walker, P. J. & Tesh, R. B., May 20 2014, In : Virology Journal. 11, 1, 97.

    Research output: Contribution to journalArticle

    Panning for molecular gold in whipworm genomes

    Ghedin, E., Jul 2014, In : Nature Genetics. 46, 7, p. 661-663 3 p.

    Research output: Contribution to journalReview article

    Potential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with Wolbachia

    Lustigman, S., Melnikow, E., Anand, S. B., Contreras, A., Nandi, V., Liu, J., Bell, A., Unnasch, T. R., Rogers, M. B. & Ghedin, E., Dec 1 2014, In : International Journal for Parasitology: Drugs and Drug Resistance. 4, 3, p. 267-277 11 p.

    Research output: Contribution to journalArticle

    Short report: Whole genome analysis of Sierra Nevada virus, a novel mononegavirus in the family Nyamiviridae

    Rogers, M. B., Cui, L., Fitch, A., Popov, V., Travassos Da Rosa, A. P. A., Vasilakis, N., Tesh, R. B. & Ghedin, E., Jul 2014, In : American Journal of Tropical Medicine and Hygiene. 91, 1, p. 159-164 6 p.

    Research output: Contribution to journalArticle

    The microbiome and the lung

    Cui, L., Morris, A., Huang, L., Beck, J. M., Twigg, H. L., Von Mutius, E. & Ghedin, E., Aug 1 2014, In : Annals of the American Thoracic Society. 11, p. S227-S232

    Research output: Contribution to journalReview article

    2013

    A Potential Role for the Interaction of Wolbachia Surface Proteins with the Brugia malayi Glycolytic Enzymes and Cytoskeleton in Maintenance of Endosymbiosis

    Melnikow, E., Xu, S., Liu, J., Bell, A. J., Ghedin, E., Unnasch, T. R. & Lustigman, S., Apr 2013, In : PLoS neglected tropical diseases. 7, 4, e2151.

    Research output: Contribution to journalArticle

    Comparative analysis of the complete genome sequence of the california msw strain of myxoma virus reveals potential host adaptations

    Kerr, P. J., Rogers, M. B., Fitch, A., DePasse, J. V., Cattadori, I. M., Hudson, P. J., Tscharke, D. C., Holmes, E. C. & Ghedin, E., 2013, In : Journal of virology. 87, 22, p. 12080-12089 10 p.

    Research output: Contribution to journalArticle

    Comparison of the respiratory microbiome in healthy nonsmokers and smokers

    Morris, A., Beck, J. M., Schloss, P. D., Campbell, T. B., Crothers, K., Curtis, J. L., Flores, S. C., Fontenot, A. P., Ghedin, E., Huang, L., Jablonski, K., Kleerup, E., Lynch, S. V., Sodergren, E., Twigg, H., Young, V. B., Bassis, C. M., Venkataraman, A., Schmidt, T. M. & Weinstock, G. M., May 15 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 10, p. 1067-1075 9 p.

    Research output: Contribution to journalArticle

    Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread

    Kerr, P. J., Rogers, M. B., Fitch, A., DePasse, J. V., Cattadori, I. M., Twaddle, A. C., Hudson, P. J., Tscharke, D. C., Read, A. F., Holmes, E. C. & Ghedin, E., Dec 2013, In : Journal of virology. 87, 23, p. 12900-12915 16 p.

    Research output: Contribution to journalArticle

    Kolente virus, a rhabdovirus species isolated from ticks and bats in the Republic of Guinea

    Ghedin, E., Rogers, M. B., Widen, S. G., Guzman, H., da Rosa, A. P. A. T., Wood, T. G., Fitch, A., Popov, V., Holmes, E. C., Walker, P. J., Vasilakis, N. & Tesh, R. B., Dec 2013, In : Journal of General Virology. 94, PART 12, p. 2609-2615 7 p.

    Research output: Contribution to journalArticle

    Mammalian adaptation in the PB2 gene of avian H5N1 influenza virus

    Min, J. Y., Santos, C., Fitch, A., Twaddle, A., Toyoda, Y., DePasse, J. V., Ghedin, E. & Subbarao, K., 2013, In : Journal of virology. 87, 19, p. 10884-10888 5 p.

    Research output: Contribution to journalArticle

    Niakha virus: A novel member of the family Rhabdoviridae isolated from phlebotomine sandflies in Senegal

    Vasilakis, N., Widen, S., Mayer, S. V., Seymour, R., Wood, T. G., Popov, V., Guzman, H., Travassos da Rosa, A. P. A., Ghedin, E., Holmes, E. C., Walker, P. J. & Tesh, R. B., Sep 2013, In : Virology. 444, 1-2, p. 80-89 10 p.

    Research output: Contribution to journalArticle

    Sequence analysis of in vivo defective interfering-like RNA of influenza a H1N1 pandemic virus

    Saira, K., Lin, X., DePasse, J. V., Halpin, R., Twaddle, A., Stockwell, T., Angus, B., Cozzi-Lepri, A., Delfino, M., Dugan, V., Dwyer, D. E., Freiberg, M., Horban, A., Losso, M., Lynfield, R., Wentworth, D. N., Holmes, E. C., Davey, R., Wentworth, D. E. & Ghedin, E., Jul 2013, In : Journal of virology. 87, 14, p. 8064-8074 11 p.

    Research output: Contribution to journalArticle

    The human mycobiome in health and disease

    Cui, L., Morris, A. & Ghedin, E., Jul 30 2013, In : Genome Medicine. 5, 7, 63.

    Research output: Contribution to journalReview article

    Use of bronchoalveolar lavage to assess the respiratory microbiome: Signal in the noise

    Twigg, H. L., Morris, A., Ghedin, E., Curtis, J. L., Huffnagle, G. B., Crothers, K., Campbell, T. B., Flores, S. C., Fontenot, A. P., Beck, J. M., Huang, L., Lynch, S., Knox, K. S. & Weinstock, G., 2013, In : The Lancet Respiratory Medicine. 1, 5, p. 354-356 3 p.

    Research output: Contribution to journalLetter

    Widespread colonization of the lung by Tropheryma whipplei in HIV infection

    Lozupone, C., Cota-Gomez, A., Palmer, B. E., Linderman, D. J., Charlson, E. S., Sodergren, E., Mitreva, M., Abubucker, S., Martin, J., Yao, G., Campbell, T. B., Flores, S. C., Ackerman, G., Stombaugh, J., Ursell, L., Beck, J. M., Curtis, J. L., Young, V. B., Lynchv, S. V., Huang, L. & 9 others, Weinstock, G. M., Knox, K. S., Twigg, H., Morris, A., Ghedin, E., Bushman, F. D., Collman, R. G., Knight, R. & Fontenot, A. P., May 15 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 10, p. 1110-1117 8 p.

    Research output: Contribution to journalArticle

    2012

    Evolutionary History and Attenuation of Myxoma Virus on Two Continents

    Kerr, P. J., Ghedin, E., DePasse, J. V., Fitch, A., Cattadori, I. M., Hudson, P. J., Tscharke, D. C., Read, A. F. & Holmes, E. C., Oct 2012, In : PLoS Pathogens. 8, 10, e1002950.

    Research output: Contribution to journalArticle

    Filarial and Wolbachia genomics

    Scott, A. L., Ghedin, E., Nutman, T. B., McReynolds, L. A., Poole, C. B., Slatko, B. E. & Foster, J. M., Feb 2012, In : Parasite Immunology. 34, 2-3, p. 121-129 9 p.

    Research output: Contribution to journalReview article

    Large-scale sequencing and the natural history of model human RNA viruses

    Dugan, V. G., Saira, K. & Ghedin, E., Jun 2012, In : Future Virology. 7, 6, p. 563-573 11 p.

    Research output: Contribution to journalReview article

    Migratory flyway and geographical distance are barriers to the gene flow of influenza virus among North American birds

    Lam, T. T. Y., Ip, H. S., Ghedin, E., Wentworth, D. E., Halpin, R. A., Stockwell, T. B., Spiro, D. J., Dusek, R. J., Bortner, J. B., Hoskins, J., Bales, B. D., Yparraguirre, D. R. & Holmes, E. C., Jan 2012, In : Ecology Letters. 15, 1, p. 24-33 10 p.

    Research output: Contribution to journalArticle

    Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission

    Ghedin, E., Holmes, E. C., Depasse, J. V., Pinilla, L. T., Fitch, A., Hamelin, M. E., Papenburg, J. & Boivin, G., Nov 15 2012, In : Journal of Infectious Diseases. 206, 10, p. 1504-1511 8 p.

    Research output: Contribution to journalArticle

    2011

    A deep sequencing approach to comparatively analyze the transcriptome of lifecycle stages of the filarial worm, brugia malayi

    Choi, Y. J., Ghedin, E., Berriman, M., McQuillan, J., Holroyd, N., Mayhew, G. F., Christensen, B. M. & Michalski, M. L., Dec 2011, In : PLoS neglected tropical diseases. 5, 12, e1409.

    Research output: Contribution to journalArticle

    Analysis of transcriptional regulation of tetracycline responsive genes in Brugia malayi

    Liu, C., Kelen, P. V., Ghedin, E., Lustigman, S. & Unnasch, T. R., Dec 2011, In : Molecular and Biochemical Parasitology. 180, 2, p. 106-111 6 p.

    Research output: Contribution to journalArticle

    Deep sequencing reveals mixed infection with 2009 pandemic influenza A (H1N1) virus strains and the emergence of oseltamivir resistance

    Ghedin, E., Laplante, J., DePasse, J., Wentworth, D. E., Santos, R. P., Lepow, M. L., Porter, J., Stellrecht, K., Lin, X., Operario, D., Griesemer, S., Fitch, A., Halpin, R. A., Stockwell, T. B., Spiro, D. J., Holmes, E. C. & St George, K., Jan 15 2011, In : Journal of Infectious Diseases. 203, 2, p. 168-174 7 p.

    Research output: Contribution to journalArticle

    Extensive geographical mixing of 2009 human H1N1 influenza a virus in a single university community

    Holmes, E. C., Ghedin, E., Halpin, R. A., Stockwell, T. B., Zhang, X. Q., Fleming, R., Davey, R., Benson, C. A., Mehta, S., Taplitz, R., Liu, Y. T., Brouwer, K. C., Wentworth, D. E., Lin, X. & Schooley, R. T., Jul 2011, In : Journal of virology. 85, 14, p. 6923-6929 7 p.

    Research output: Contribution to journalArticle

    Genomic and protein structural maps of adaptive evolution of human influenza a virus to increased virulence in the mouse

    Ping, J., Keleta, L., Forbes, N. E., Dankar, S., Stecho, W., Tyler, S., Zhou, Y., Babiuk, L., Weingartl, H., Halpin, R. A., Boyne, A., Bera, J., Hostetler, J., Fedorova, N. B., Proudfoot, K., Katzel, D. A., Stockwell, T. B., Ghedin, E., Spiro, D. J. & Brown, E. G., 2011, In : PloS one. 6, 6, e21740.

    Research output: Contribution to journalArticle

    Interaction of a Wolbachia WSP-like protein with a nuclear-encoded protein of Brugia malayi

    Melnikow, E., Xu, S., Liu, J., Li, L., Oksov, Y., Ghedin, E., Unnasch, T. R. & Lustigman, S., Aug 15 2011, In : International Journal for Parasitology. 41, 10, p. 1053-1061 9 p.

    Research output: Contribution to journalArticle

    In vivo transfection of developmentally competent Brugia malayi infective larvae

    Xu, S., Liu, C., Tzertzinis, G., Ghedin, E., Evans, C. C., Kaplan, R. & Unnasch, T. R., 2011, In : International Journal for Parasitology. 41, 3, p. 355-362 8 p.

    Research output: Contribution to journalArticle

    It's a small world after all - Viral genomics and the global dominance of viruses

    Ghedin, E. & Upton, C., Oct 2011, In : Current Opinion in Virology. 1, 4, p. 280-281 2 p.

    Research output: Contribution to journalEditorial

    Molecular characterization of a new species in the genus Alphacoronavirus associated with mink epizootic catarrhal gastroenteritis

    Vlasova, A. N., Halpin, R., Wang, S., Ghedin, E., Spiro, D. J. & Saif, L. J., Jun 2011, In : Journal of General Virology. 92, 6, p. 1369-1379 11 p.

    Research output: Contribution to journalArticle

    Phylogeography of the spring and fall waves of the H1N1/09 pandemic influenza virus in the United States

    Nelson, M. I., Tan, Y., Ghedin, E., Wentworth, D. E., George, K. S., Edelman, L., Beck, E. T., Fan, J., Lam, T. T. Y., Kumar, S., Spiro, D. J., Simonsen, L., Viboud, C., Holmes, E. C., Henrickson, K. J. & Musser, J. M., Jan 2011, In : Journal of virology. 85, 2, p. 828-834 7 p.

    Research output: Contribution to journalArticle

    Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia

    Bennuru, S., Meng, Z., Ribeiro, J. M. C., Semnani, R. T., Ghedin, E., Chan, K., Lucas, D. A., Veenstra, T. D. & Nutman, T. B., Jun 7 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 23, p. 9649-9654 6 p.

    Research output: Contribution to journalArticle

    Temporally structured metapopulation dynamics and persistence of influenza A H3N2 virus in humans

    Bahl, J., Nelson, M. I., Chan, K. H., Chen, R., Vijaykrishna, D., Halpin, R. A., Stockwell, T. B., Lin, X., Wentworth, D. E., Ghedin, E., Guan, Y., Peiris, J. S. M., Riley, S., Rambaut, A., Holmes, E. C. & Smith, G. J. D., Nov 29 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 48, p. 19359-19364 6 p.

    Research output: Contribution to journalArticle

    The human lung microbiome

    Losada, L., Ghedin, E., Morris, A., Chu, H. W. & Nierman, W. C., 2011, Metagenomics of the Human Body. Springer New York, p. 117-143 27 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2010

    Functional analysis of putative operons in Brugia malayi

    Liu, C., Oliveira, A., Chauhan, C., Ghedin, E. & Unnasch, T. R., Jan 2010, In : International Journal for Parasitology. 40, 1, p. 63-71 9 p.

    Research output: Contribution to journalArticle

    Unseasonal transmission of H3N2 influenza A virus during the swine-origin H1N1 pandemic

    Ghedin, E., Wentworth, D. E., Halpin, R. A., Lin, X., Bera, J., DePasse, J., Fitch, A., Griesemer, S., Hine, E., Katzel, D. A., Overton, L., Proudfoot, K., Sitz, J., Szczypinski, B., St George, K., Spiro, D. J. & Holmes, E. C., Jun 2010, In : Journal of virology. 84, 11, p. 5715-5718 4 p.

    Research output: Contribution to journalArticle

    2009

    A multi-reservoir model of influenza evolution

    Dreisigmeyer, D. W., Rosenfeld, R., DePasse, J. V., Ghedin, E., Price, I. & Clermont, G., 2009, In : J Crit Care. 24, 3, p. e33-e34

    Research output: Contribution to journalArticle

    Brugia malayi gene expression in response to the targeting of the Wolbachia endosymbiont by tetracycline treatment

    Ghedin, E., Hailemariam, T., DePasse, J. V., Zhang, X., Oksov, Y., Unnasch, T. R. & Lustigman, S., Oct 2009, PLoS Neglected Tropical Diseases. 10 ed. Vol. 3. e525

    Research output: Chapter in Book/Report/Conference proceedingChapter