Research output per year
Research output per year
- 1 - 50 out of 299 results
Search results
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2023
An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept
Boender, A. J., Boon, M., Elliott Albers, H., Eck, S. R., Fricker, B. A., Kelly, A. M., LeDoux, J. E., Motta, S. C., Shrestha, P., Taylor, J. H., Trainor, B. C., Rio, R. T. D. & Young, L. J., Jun 2 2023, In: Science Advances. 9, 22, eadf4950.Research output: Contribution to journal › Article › peer-review
Open Access -
Deep history and beyond: a reply to commentators
LeDoux, J., 2023, In: Philosophical Psychology. 36, 4, p. 756-766 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Joseph LeDoux
LeDoux, J., Jan 23 2023, In: Current biology : CB. 33, 2, p. R48-R50Research output: Contribution to journal › Article › peer-review
Open Access -
The Deep History of Ourselves: The Four-Billion-Year Story of How We Got Conscious Brains
LeDoux, J., 2023, In: Philosophical Psychology. 36, 4, p. 704-715 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Temporally and anatomically specific contributions of the human amygdala to threat and safety learning
Wen, Z., Raio, C. M., Pace-Schott, E. F., Lazar, S. W., LeDoux, J. E., Phelps, E. A. & Milad, M. R., Jun 28 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 26, e2204066119.Research output: Contribution to journal › Article › peer-review
Open Access -
The mnemonic basis of subjective experience
Lau, H., Michel, M., LeDoux, J. E. & Fleming, S. M., Aug 2022, In: Nature Reviews Psychology. 1, 8, p. 479-488 10 p.Research output: Contribution to journal › Article › peer-review
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2021
Conditional Control of Instrumental Avoidance by Context Following Extinction
Campese, V. D., Brannigan, L. A. & LeDoux, J. E., Sep 28 2021, In: Frontiers in Behavioral Neuroscience. 15, 730113.Research output: Contribution to journal › Article › peer-review
Open Access -
Correlation between rostral dorsomedial prefrontal cortex activation by trauma-related words and subsequent response to cbt for ptsd
Weisholtz, D., Silbersweig, D., Pan, H., Cloitre, M., Ledoux, J. & Stern, E., Mar 1 2021, In: Journal of Neuropsychiatry and Clinical Neurosciences. 33, 2, p. 116-123 8 p.Research output: Contribution to journal › Article › peer-review
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Observation of others’ threat reactions recovers memories previously shaped by firsthand experiences
Haaker, J., Diaz-Mataix, L., Guillazo-Blanch, G., Stark, S. A., Kern, L., LeDoux, J. E. & Olsson, A., Jul 27 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 30, e2101290118.Research output: Contribution to journal › Article › peer-review
Open Access -
The extra ingredient
Brown, R., LeDoux, J. & Rosenthal, D., Apr 2021, In: Biology and Philosophy. 36, 2, 16.Research output: Contribution to journal › Article › peer-review
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Upregulation of eIF4E, but not other translation initiation factors, in dendritic spines during memory formation
Gindina, S., Botsford, B., Cowansage, K., LeDoux, J., Klann, E., Hoeffer, C. & Ostroff, L., Aug 1 2021, In: Journal of Comparative Neurology. 529, 11, p. 3112-3126 15 p.Research output: Contribution to journal › Article › peer-review
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What emotions might be like in other animals
LeDoux, J. E., Jul 12 2021, In: Current Biology. 31, 13, p. R824-R829Research output: Contribution to journal › Article › peer-review
Open Access -
2020
A brainstem-central amygdala circuit underlies defensive responses to learned threats
Gu, Y., Piper, W. T., Branigan, L. A., Vazey, E. M., Aston-Jones, G., Lin, L., LeDoux, J. E. & Sears, R. M., Mar 1 2020, In: Molecular Psychiatry. 25, 3, p. 640-654 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation
Shrestha, P., Ayata, P., Herrero-Vidal, P., Longo, F., Gastone, A., LeDoux, J. E., Heintz, N. & Klann, E., Feb 1 2020, In: Nature Neuroscience. 23, 2, p. 281-292 12 p.Research output: Contribution to journal › Article › peer-review
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Higher-order memory schema and consciousness experience
Brown, R. & LeDoux, J., May 18 2020, In: Cognitive Neuropsychology. 37, 3-4, p. 213-215 3 p.Research output: Contribution to journal › Article › peer-review
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How does the non-conscious become conscious?
LeDoux, J. E., Mar 9 2020, In: Current Biology. 30, 5, p. R196-R199Research output: Contribution to journal › Article › peer-review
Open Access -
Motivational factors underlying aversive Pavlovian-instrumental transfer
Campese, V. D., Kim, I. T., Kurpas, B., Branigan, L., Draus, C. & LeDoux, J. E., Nov 2020, In: Learning and Memory. 27, 11, p. 477-482 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The bed nucleus of the stria terminalis and functionally linked neurocircuitry modulate emotion processing and HPA axis dysfunction in posttraumatic stress disorder
Awasthi, S., Pan, H., LeDoux, J. E., Cloitre, M., Altemus, M., McEwen, B., Silbersweig, D. & Stern, E., Jan 2020, In: NeuroImage: Clinical. 28, 102442.Research output: Contribution to journal › Article › peer-review
Open Access -
Thoughtful feelings
LeDoux, J. E., Jun 8 2020, In: Current Biology. 30, 11, p. R619-R623Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Axon TRAP reveals learning-associated alterations in cortical axonal mRNAs in the lateral amgydala
Ostroff, L. E., Santini, E., Sears, R., Deane, Z., Kanadia, R. N., Ledoux, J. E., Lhakhang, T., Tsirigos, A., Heguy, A. & Klann, E., Dec 2019, In: eLife. 8, e51607.Research output: Contribution to journal › Article › peer-review
Open Access -
Chemogenetic inhibition reveals that processing relative but not absolute threat requires basal amygdala
Campese, V. D., Kim, I. T., Hou, M., Gupta, S., Draus, C., Kurpas, B., Burke, K. & LeDoux, J. E., Oct 23 2019, In: Journal of Neuroscience. 39, 43, p. 8510-8516 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of threat expression following infant maltreatment: Infant and adult enhancement but adolescent attenuation
Junod, A., Opendak, M., LeDoux, J. E. & Sullivan, R. M., May 22 2019, In: Frontiers in Behavioral Neuroscience. 13, 130.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Activation of a novel p70 S6 kinase 1-dependent intracellular cascade in the basolateral nucleus of the amygdala is required for the acquisition of extinction memory
Huynh, T. N., Santini, E., Mojica, E., Fink, A. E., Hall, B. S., Fetcho, R. N., Grosenick, L., Deisseroth, K., Ledoux, J. E., Liston, C. & Klann, E., Jun 1 2018, In: Molecular Psychiatry. 23, 6, p. 1394-1401 8 p.Research output: Contribution to journal › Article › peer-review
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A principled method to identify individual differences and behavioral shifts in signaled active avoidance
Krypotos, A. M., Moscarello, J. M., Sears, R. M., LeDoux, J. E. & Galatzer-Levy, I., Nov 2018, In: Learning and Memory. 25, 11, p. 564-568 5 p.Research output: Contribution to journal › Article › peer-review
Open Access -
β-adrenergic enhancement of neuronal excitability in the lateral amygdala is developmentally gated
Fink, A. E. & LeDoux, J. E., May 2018, In: Journal of neurophysiology. 119, 5, p. 1658-1664 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Accumulation of polyribosomes in dendritic spine heads, but not bases and necks, during memory consolidation depends on cap-dependent translation initiation
Ostroff, L. E., Botsford, B., Gindina, S., Cowansage, K. K., Ledoux, J. E., Klann, E. & Hoeffer, C., Feb 15 2017, In: Journal of Neuroscience. 37, 7, p. 1862-1872 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Active avoidance: Neural mechanisms and attenuation of pavlovian conditioned responding
Boeke, E. A., Moscarello, J. M., LeDoux, J. E., Phelps, E. A. & Hartley, C. A., May 3 2017, In: Journal of Neuroscience. 37, 18, p. 4808-4818 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A higher-order theory of emotional consciousness
Ledoux, J. E. & Brown, R., Mar 7 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 10, p. E2016-E2025Research output: Contribution to journal › Article › peer-review
Open Access -
Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations
Díaz-Mataix, L., Piper, W. T., Schiff, H. C., Roberts, C. H., Campese, V. D., Sears, R. M. & LeDoux, J. E., Sep 2017, In: Learning and Memory. 24, 9, p. 432-439 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Noradrenergic regulation of central amygdala in aversive pavlovian-to-instrumental transfer
Campese, V. D., Soroeta, J. M., Vazey, E. M., Aston-Jones, G., Ledoux, J. E. & Sears, R. M., Sep 1 2017, In: eNeuro. 4, 5, e0224-17.2017.Research output: Contribution to journal › Article › peer-review
Open Access -
Pavlovian extinction and recovery effects in aversive pavlovian to instrumental transfer
Campese, V. D., Kim, I. T., Rojas, G. & Ledoux, J. E., Sep 25 2017, In: Frontiers in Behavioral Neuroscience. 11, 179.Research output: Contribution to journal › Article › peer-review
Open Access -
Primary auditory cortex regulates threat memory specificity
Wigestrand, M. B., Schiff, H. C., Fyhn, M., LeDoux, J. E. & Sears, R. M., Jan 2017, In: Learning and Memory. 24, 1, p. 55-58 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Updating of aversive memories after temporal error detection is differentially modulated by mTOR across development
Tallot, L., Diaz-Mataix, L., Perry, R. E., Wood, K., LeDoux, J. E., Mouly, A. M., Sullivan, R. M. & Doyère, V., Mar 2017, In: Learning and Memory. 24, 3, p. 115-122 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Updating temporal expectancy of an aversive event engages striatal plasticity under amygdala control
Dallérac, G., Graupner, M., Knippenberg, J., Martinez, R. C. R., Tavares, T. F., Tallot, L., El Massioui, N., Verschueren, A., Höhn, S., Bertolus, J. B., Reyes, A., LeDoux, J. E., Schafe, G. E., Diaz-Mataix, L. & Doyère, V., Jan 9 2017, In: Nature communications. 8, 13920.Research output: Contribution to journal › Article › peer-review
Open Access -
β-Adrenergic Receptors Regulate the Acquisition and Consolidation Phases of Aversive Memory Formation Through Distinct, Temporally Regulated Signaling Pathways
Schiff, H. C., Johansen, J. P., Hou, M., Bush, D. E. A., Smith, E. K., Klein, J. A. E., LeDoux, J. E. & Sears, R. M., Mar 1 2017, In: Neuropsychopharmacology. 42, 4, p. 895-903 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Evaluation of ambiguous associations in the amygdala by learning the structure of the environment
Madarasz, T. J., Diaz-Mataix, L., Akhand, O., Ycu, E. A., LeDoux, J. E. & Johansen, J. P., Jul 1 2016, In: Nature Neuroscience. 19, 7, p. 965-972 8 p.Research output: Contribution to journal › Article › peer-review
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The neural foundations of reaction and action in aversive motivation
Campese, V. D., Sears, R. M., Moscarello, J. M., Diaz-Mataix, L., Cain, C. K. & LeDoux, J. E., Jun 1 2016, In: Current Topics in Behavioral Neurosciences. 27, p. 171-195 25 p.Research output: Contribution to journal › Article › peer-review
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2015
Active avoidance requires a serial basal amygdala to nucleus accumbens shell circuit
Ramirez, F., Moscarello, J. M., Le Doux, J. E. & Sears, R. M., 2015, In: Journal of Neuroscience. 35, 8, p. 3470-3477 8 p.Research output: Contribution to journal › Article › peer-review
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Beyond the amygdala: Linguistic threat modulates peri-sylvian semantic access cortices
Weisholtz, D. S., Root, J. C., Butler, T., Tüscher, O., Epstein, J., Pan, H., Protopopescu, X., Goldstein, M., Isenberg, N., Brendel, G., LeDoux, J., Silbersweig, D. A. & Stern, E., Dec 1 2015, In: Brain and Language. 151, p. 12-22 11 p.Research output: Contribution to journal › Article › peer-review
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Feelings: What are they & how does the brain make them?
Ledoux, J. E., Jan 21 2015, In: Daedalus. 144, 1, p. 96-111 16 p.Research output: Contribution to journal › Article › peer-review
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Modulation of instrumental responding by a conditioned threat stimulus requires lateral and central amygdala
Campese, V. D., Gonzaga, R., Moscarello, J. M. & LeDoux, J. E., Oct 30 2015, In: Frontiers in Behavioral Neuroscience. 9, OCTOBER, 293.Research output: Contribution to journal › Article › peer-review
Open Access -
Outcome in place of an expected threat diminishes recovery of defensive responses
Dunsmoor, J. E., Campese, V. D., Ceceli, A. O., LeDoux, J. E. & Phelps, E. A., 2015, In: Biological Psychiatry. 78, 3, p. 203-209 7 p.Research output: Contribution to journal › Article › peer-review
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2014
A Conversation with Joseph LeDoux
LeDoux, J. & Narain, C., 2014, In: Cold Spring Harbor symposia on quantitative biology. 79, p. 279-281 3 p.Research output: Contribution to journal › Article › peer-review
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Diverse effects of conditioned threat stimuli on behavior
Moscarello, J. M. & Ledoux, J., 2014, In: Cold Spring Harbor symposia on quantitative biology. 79, p. 11-19 9 p.Research output: Contribution to journal › Article › peer-review
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Extinction resistant changes in the human auditory association cortex following threat learning
Apergis-Schoute, A. M., Schiller, D., LeDoux, J. E. & Phelps, E. A., Sep 2014, In: Neurobiology of Learning and Memory. 113, p. 109-114 6 p.Research output: Contribution to journal › Article › peer-review
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Hebbian and neuromodulatory mechanisms interact to trigger associative memory formation
Johansen, J. P., Diaz-Mataix, L., Hamanaka, H., Ozawa, T., Ycu, E., Koivumaa, J., Kumar, A., Hou, M., Deisseroth, K., Boyden, E. S. & LeDoux, J. E., Dec 23 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. E5584-E5592Research output: Contribution to journal › Article › peer-review
Open Access -
Heterogeneity in signaled active avoidance learning: Substantive and methodological relevance of diversity in instrumental defensive responses to threat cues
Galatzer-Levy, I. R., Moscarello, J., Blessing, E. M., Klein, J. A., Cain, C. K. & LeDoux, J. E., Sep 24 2014, In: Frontiers in Systems Neuroscience. 8, SEP, 179.Research output: Contribution to journal › Article › peer-review
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Lesions of lateral or central amygdala abolish aversive Pavlovian-to-instrumental transfer in rats
Campese, V. D., Kim, J., Lázaro-Muñoz, G., Pena, L., Ledoux, J. E. & Cain, C. K., May 7 2014, In: Frontiers in Behavioral Neuroscience. 8, MAY, 161.Research output: Contribution to journal › Article › peer-review
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Medial amygdala lesions selectively block aversive pavlovian-instrumental transfer in rats
McCue, M. G., LeDoux, J. E. & Cain, C. K., Sep 18 2014, In: Frontiers in Behavioral Neuroscience. 8, 329.Research output: Contribution to journal › Article › peer-review
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Novelty-facilitated extinction: Providing a novel outcome in place of an expected threat diminishes recovery of defensive responses
Dunsmoor, J. E., Campese, V. D., Ceceli, A. O., Ledoux, J. & Phelps, E., 2014, In: Biological Psychiatry. 78, 3, p. 203-209Research output: Contribution to journal › Article › peer-review