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Rafael Song

Assistant Professor

    19952020

    Research output per year

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    Research Output

    2020

    A multi-well based detection platform with integrated PDMS concentrators for rapid multiplexed enzymatic assays

    Wei, X. & Song, Y. A., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 655-656 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Microfluidic Electrokinetic Preconcentration Chips: Enhancing the detection of nucleic acids and exosomes

    Kim, J., Sahloul, S., Orozaliev, A., Do, V. Q., Pham, V. S., Martins, D., Wei, X., Levicky, R. & Song, Y. A., Apr 2020, In : IEEE Nanotechnology Magazine. 14, 2, p. 18-34 17 p., 8986548.

    Research output: Contribution to journalArticle

    Microfluidic Trojan Design in Flow-based Biochips

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., Mar 2020, Proceedings of the 2020 Design, Automation and Test in Europe Conference and Exhibition, DATE 2020. Di Natale, G., Bolchini, C. & Vatajelu, E-I. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 1037-1042 6 p. 9116225. (Proceedings of the 2020 Design, Automation and Test in Europe Conference and Exhibition, DATE 2020).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Quantitative fluorescence imaging of mitochondria in body wall muscles of Caenorhabditis elegans under hyperglycemic conditions using a microfluidic chip

    Sofela, S., Sahloul, S., Bhattacharjee, S., Bose, A., Usman, U. & Song, Y. A., Jun 19 2020, In : Integrative Biology. 12, 6, p. 150-160 11 p.

    Research output: Contribution to journalArticle

    Rapid detection of exosomes & exosomal micro RNA biomarkers by electrokinetic concentration for liquid biopsy on chip

    Cheung, L., Wei, X., Martins, D. & Song, Y. A., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 1275-1276 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Synchronization of C. Elegans through high-throughput separation of eggs in a spiral microfluidic chip

    Sofela, S., Sahloul, S., Kwon, T., Han, J., Warkiani, M. E. & Song, Y. A., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 1100-1101 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2019

    A Fully differential potentiostat circuit with integrated time-based adcs

    Subhan, S., Khapli, S., Song, Y. A. & Ha, S., Oct 2019, BioCAS 2019 - Biomedical Circuits and Systems Conference, Proceedings. Institute of Electrical and Electronics Engineers Inc., 8919031. (BioCAS 2019 - Biomedical Circuits and Systems Conference, Proceedings).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Can Multi-Layer Microfluidic Design Methods Aid Bio-Intellectual Property Protection?

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., Jul 2019, 2019 IEEE 25th International Symposium on On-Line Testing and Robust System Design, IOLTS 2019. Gizopoulos, D., Alexandrescu, D., Papavramidou, P. & Maniatakos, M. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 151-154 4 p. 8854393. (2019 IEEE 25th International Symposium on On-Line Testing and Robust System Design, IOLTS 2019).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Desieve the Attacker: Thwarting IP Theft in Sieve-Valve-based Biochips

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., May 14 2019, Proceedings of the 2019 Design, Automation and Test in Europe Conference and Exhibition, DATE 2019. Institute of Electrical and Electronics Engineers Inc., p. 210-215 6 p. 8715094. (Proceedings of the 2019 Design, Automation and Test in Europe Conference and Exhibition, DATE 2019).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Phenotyping of the thrashing forces exerted by partially immobilized: C. elegans using elastomeric micropillar arrays

    Sofela, S., Sahloul, S., Stubbs, C., Orozaliev, A., Refai, F. S., Esmaeel, A. M., Fahs, H., Abdelgawad, M. O., Gunsalus, K. C. & Song, Y. A., Nov 7 2019, In : Lab on a Chip. 19, 21, p. 3685-3696 12 p.

    Research output: Contribution to journalArticle

    Security assessment of microfluidic fully-programmable-valve-array biochips

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., May 9 2019, Proceedings - 32nd International Conference on VLSI Design, VLSID 2019 - Held concurrently with 18th International Conference on Embedded Systems, ES 2019. Institute of Electrical and Electronics Engineers Inc., p. 197-202 6 p. 8710987. (Proceedings - 32nd International Conference on VLSI Design, VLSID 2019 - Held concurrently with 18th International Conference on Embedded Systems, ES 2019).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Security assessment of microfluidic immunoassays

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., 2019, p. 217-222. 6 p.

    Research output: Contribution to conferencePaper

    Toward Secure Microfluidic Fully Programmable Valve Array Biochips

    Shayan, M., Bhattacharjee, S., Song, Y. A., Chakrabarty, K. & Karri, R., Dec 2019, In : IEEE Transactions on Very Large Scale Integration (VLSI) Systems. 27, 12, p. 2755-2766 12 p., 8764604.

    Research output: Contribution to journalArticle

    2018

    A Multiwell-Based Detection Platform with Integrated PDMS Concentrators for Rapid Multiplexed Enzymatic Assays

    Wei, X., Do, V. Q., Pham, S. V., Martins, D. & Song, Y. A., Dec 1 2018, In : Scientific reports. 8, 1, 10772.

    Research output: Contribution to journalArticle

    A single pressure pulse-actuated 3D-printed microfluidic tip for high throughput dispensing of C. elegans worms

    Chaturvedi, N., Baban, N. S., Sofela, S. O., Orozaliev, A., Giakoumidis, N., Kim, J., Gunsalus, K. C. & Song, Y. A., Jan 1 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1557-1559 3 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    High-throughput sorting of eggs for synchronization of: C. elegans in a microfluidic spiral chip

    Sofela, S., Sahloul, S., Rafeie, M., Kwon, T., Han, J., Warkiani, M. E. & Song, Y. A., Feb 21 2018, In : Lab on a Chip. 18, 4, p. 679-687 9 p.

    Research output: Contribution to journalArticle

    Mechanistic approach to mimic lizard tail autotomy using deformable microstructures as biological interlock in the soft tissue

    Baban, N. S., Orozaliev, A. & Song, Y. A., Jan 1 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1670-1672 3 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Polyaniline-functionalized ion-sensitive floating-gate FETs for the on-chip monitoring of peroxidase-catalyzed redox reactions

    Zhang, Q., Kaisti, M., Prabhu, A., Yu, Y., Song, Y. A., Rafailovich, M. H., Rahman, A. & Levon, K., Jan 20 2018, In : Electrochimica Acta. 261, p. 256-264 9 p.

    Research output: Contribution to journalArticle

    Quantitative analysis of muscle atrophy under hyperglycemic conditions using C. Elegans model in a scalable microfluidic device

    Sofela, S., Orozaliev, A., Sahloul, S., Chaturvedi, N., Shahjerdi, D. & Song, Y. A., Jan 1 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 122-125 4 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 1).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Rapid detection and trapping of extracellular vesicles by electrokinetic concentration for liquid biopsy on chip

    Cheung, L. S., Sahloul, S., Orozaliev, A. & Song, Y. A., Jun 19 2018, In : Micromachines. 9, 6, 306.

    Research output: Contribution to journalArticle

    Rapid detection and trapping of extracellular vesicles by electrokinetic preconcentration for liquid biopsy

    Cheung, L., Sahloul, S., Orozaliev, A. & Song, Y. A., Jan 1 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1413-1416 4 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Rapid detection and trapping of extracellular vesicles by electrokinetic preconcentration for liquid biopsy

    Cheung, L., Sahloul, S., Orozaliev, A. & Song, Y. A., 2018, 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018. Chemical and Biological Microsystems Society, p. 1413-1416 4 p. (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Rapid detection of exosomal microRNA biomarkers by electrokinetic concentration for liquid biopsy on chip

    Cheung, L. S., Wei, X., Martins, D. & Song, Y. A., Jan 1 2018, In : Biomicrofluidics. 12, 1, 014104.

    Research output: Contribution to journalArticle

    2017

    Detecting and Trapping of a Single C. elegans Worm in a Microfluidic Chip for Automated Microplate Dispensing

    Desta, I. T., Al-Sharif, A., AlGharibeh, N., Mustafa, N., Orozaliev, A., Giakoumidis, N., Gunsalus, K. C. & Song, Y. A., Aug 1 2017, In : SLAS Technology. 22, 4, p. 431-436 6 p.

    Research output: Contribution to journalArticle

    2016

    Accelerating the mass transport of DNA biomolecules onto DNA microarray for enhanced detection by electrokinetic concentration in a microfluidic chip

    Martins, D., Wei, X., Levicky, R. & Song, Y. A., 2016, Micro/Nanofluidics and Lab-on-a-Chip; Nanofluids; Micro/Nanoscale Interfacial Transport Phenomena; Micro/Nanoscale Boiling and Condensation Heat Transfer; Micro/Nanoscale Thermal Radiation; Micro/Nanoscale Energy Devices and Systems. American Society of Mechanical Engineers, V001T01A007. (ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer, MNHMT 2016; vol. 1).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Creating sub-50 Nm nanofluidic junctions in PDMS microfluidic chip via self-assembly process of colloidal particles

    Wei, X., Syed, A., Mao, P., Han, J. & Song, Y. A., Mar 13 2016, In : Journal of Visualized Experiments. 2016, 109, e54145.

    Research output: Contribution to journalArticle

    Increasing the detection sensitivity for dnamorpholino hybridization in sub-nanomolar regime by enhancing the surface ion conductance of PEDOT: PSS membrane in a microchannel

    Wei, X., Zhang, Q. & Song, Y. A., 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 896-897 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    2015
    2014

    Creating sub-50 nm nanofluidic junctions in a PDMS microchip via self-assembly process of colloidal silica beads for electrokinetic concentration of biomolecules

    Syed, A., Mangano, L., Mao, P., Han, J. & Song, Y. A., Dec 7 2014, In : Lab on a Chip. 14, 23, p. 4455-4460 6 p.

    Research output: Contribution to journalArticle

    2013

    Microfabricated nerve-electrode interfaces in neural prosthetics and neural engineering

    Song, Y. A., Ibrahim, A. M. S., Rabie, A. N., Han, J. & Lin, S. J., Oct 1 2013, In : Biotechnology and Genetic Engineering Reviews. 29, 2, p. 113-134 22 p.

    Research output: Contribution to journalArticle

    Tunable membranes for free-flow zone electrophoresis in PDMS microchip using guided self-assembly of silica microbeads

    Song, Y. A., Wu, L., Tannenbaum, S. R., Wishnok, J. S. & Han, J., Dec 17 2013, In : Analytical chemistry. 85, 24, p. 11695-11699 5 p.

    Research output: Contribution to journalArticle

    2012

    Nanofluidic preconcentration device in a straight microchannel using ion concentration polarization

    Ko, S. H., Song, Y. A., Kim, S. J., Kim, M., Han, J. & Kang, K. H., Nov 7 2012, In : Lab on a Chip. 12, 21, p. 4472-4482 11 p.

    Research output: Contribution to journalArticle

    Nanotechnology in plastic surgery

    Ibrahim, A. M. S., Gerstle, T. L., Rabie, A. N., Song, Y. A., Melik, R., Han, J. & Lin, S. J., Dec 2012, In : Plastic and reconstructive surgery. 130, 6, p. 879e-887e

    Research output: Contribution to journalArticle

    2011

    Electrochemical activation and inhibition of neuromuscular systems through modulation of ion concentrations with ion-selective membranes

    Song, Y. A., Melik, R., Rabie, A. N., Ibrahim, A. M. S., Moses, D., Tan, A., Han, J. & Lin, S. J., Dec 2011, In : Nature Materials. 10, 12, p. 980-986 7 p.

    Research output: Contribution to journalArticle

    Enhancing/multiplexing protease assay with droplet based microfluidics using biomolecule concentrator

    Chen, C. H., Sarkar, A., Song, Y. A., Miller, M. A., Kim, S. J., Griffith, L. G., Lauffenburger, D. A. & Han, J., 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. p. 2080-2082 3 p. (15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011; vol. 3).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator

    Chen, C. H., Sarkar, A., Song, Y. A., Miller, M. A., Kim, S. J., Griffith, L. G., Lauffenburger, D. A. & Han, J., Jul 13 2011, In : Journal of the American Chemical Society. 133, 27, p. 10368-10371 4 p.

    Research output: Contribution to journalArticle

    2010

    Capillary-valve-based fabrication of ion-selective membrane junction for electrokinetic sample preconcentration in PDMS chip

    Liu, V., Song, Y. A. & Han, J., 2010, In : Lab on a Chip. 10, 11, p. 1485-1490 6 p.

    Research output: Contribution to journalArticle

    Free-flow zone electrophoresis of peptides and proteins in PDMS microchip for narrow pi range sample prefractionation coupled with mass spectrometry

    Song, Y. A., Chan, M., Cello, C., Tannenbaum, S. R., Wishnok, J. S. & Han, J., Mar 15 2010, In : Analytical chemistry. 82, 6, p. 2317-2325 9 p.

    Research output: Contribution to journalArticle

    Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: Theory, fabrication, and applications

    Kim, S. J., Song, Y. A. & Han, J., Feb 24 2010, In : Chemical Society Reviews. 39, 3, p. 912-922 11 p.

    Research output: Contribution to journalArticle

    2008

    Encapsulation of biomolecules with programmable concentrations in microdroplets using electrokinetic concentrator

    Song, Y. A., Sarkar, A. & Han, J., 2008, p. 1420-1422. 3 p.

    Research output: Contribution to conferencePaper

    High-throughput sample preparation for mass spectrometry by continuousflow pi-based fractionation of peptides and proteins

    Song, Y. A. & Han, J., 2008, p. 1323-1325. 3 p.

    Research output: Contribution to conferencePaper

    Increase of reaction rate and sensitivity of low-abundance enzyme assay using micro/nanofluidic preconcentration chip

    Lee, J. H., Song, Y. A., Tannenbaum, S. R. & Han, J., May 1 2008, In : Analytical chemistry. 80, 9, p. 3198-3204 7 p.

    Research output: Contribution to journalArticle

    Multiplexed proteomic sample preconcentration device using surface-patterned ion-selective membrane

    Lee, J. H., Song, Y. A. & Han, J., 2008, In : Lab on a Chip. 8, 4, p. 596-601 6 p.

    Research output: Contribution to journalArticle

    Rapid fabrication of microfluidic polymer electrolyte membrane fuel cell in PDMS by surface patterning of perfluorinated ion-exchange resin

    Song, Y. A., Batista, C., Sarpeshkar, R. & Han, J., Sep 1 2008, In : Journal of Power Sources. 183, 2, p. 674-677 4 p.

    Research output: Contribution to journalArticle

    2006

    Continuous-flow pI-based sorting of proteins and peptides in a microfluidic chip using diffusion potential

    Song, Y. A., Hsu, S., Stevens, A. L. & Han, J., Jun 1 2006, In : Analytical chemistry. 78, 11, p. 3528-3536 9 p.

    Research output: Contribution to journalArticle

    Electrohydrodynamic generation and delivery of monodisperse picoliter droplets using a poly(dimethylsiloxane) microchip

    Sung, J. K., Song, Y. A., Skipper, P. L. & Han, J., Dec 1 2006, In : Analytical chemistry. 78, 23, p. 8011-8019 9 p.

    Research output: Contribution to journalArticle

    Experimental investigations into rapid prototyping of composites by novel hybrid deposition process

    Song, Y. A. & Park, S., Jan 10 2006, In : Journal of Materials Processing Technology. 171, 1, p. 35-40 6 p.

    Research output: Contribution to journalArticle