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Thomas Carew

Professor of Neural Science & Psychology

    1969 …2020

    Research output per year

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    Research Output

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    Article
    2020
    Open Access
    Open Access
    2019

    Neurotropic and modulatory effects of insulin-like growth factor II in Aplysia

    Kukushkin, N. V., Williams, S. P. & Carew, T. J., Dec 1 2019, In : Scientific reports. 9, 1, 14379.

    Research output: Contribution to journalArticle

    Open Access

    The ELAV family of RNA-binding proteins in synaptic plasticity and long-term memory

    Mirisis, A. A. & Carew, T. J., May 2019, In : Neurobiology of Learning and Memory. 161, p. 143-148 6 p.

    Research output: Contribution to journalArticle

    2016

    Transforming growth factor β recruits persistent MAPK signaling to regulate long-term memory consolidation in Aplysia californica

    Shobe, J., Philips, G. T. & Carew, T. J., May 2016, In : Learning and Memory. 23, 5, p. 182-188 7 p.

    Research output: Contribution to journalArticle

    2015

    Distinct Growth Factor Families Are Recruited in Unique Spatiotemporal Domains during Long-Term Memory Formation in Aplysia californica

    Kopec, A. M., Philips, G. T. & Carew, T. J., Jun 3 2015, In : Neuron. 86, 5, p. 1228-1239 12 p.

    Research output: Contribution to journalArticle

    2014

    A novel cysteine-rich neurotrophic factor in Aplysia facilitates growth, MAPK activation, and long-term synaptic facilitation

    Pu, L., Kopec, A. M., Boyle, H. D. & Carew, T. J., Apr 2014, In : Learning and Memory. 21, 4, p. 215-222 8 p.

    Research output: Contribution to journalArticle

    2013

    Mapk establishes a molecular context that defines effective training patterns for long-term memory formation

    Philips, G. T., Ye, X., Kopec, A. M. & Carew, T. J., Apr 24 2013, In : Journal of Neuroscience. 33, 17, p. 7565-7573 9 p.

    Research output: Contribution to journalArticle

    Pattern and predictability in memory formation: From molecular mechanisms to clinical relevance

    Philips, G. T., Kopec, A. M. & Carew, T. J., Oct 1 2013, In : Neurobiology of Learning and Memory. 105, p. 117-124 8 p.

    Research output: Contribution to journalArticle

    2012
    2011

    The tail-elicited tail withdrawal reflex of Aplysia is mediated centrally at tail sensory-motor synapses and exhibits sensitization across multiple temporal domains

    Philips, G. T., Sherff, C. M., Menges, S. A. & Carew, T. J., Apr 1 2011, In : Learning and Memory. 18, 4, p. 272-282 11 p.

    Research output: Contribution to journalArticle

    2010

    A novel postsynaptic mechanism for heterosynaptic sharing of short-term plasticity

    Reissner, K. J., Pu, L., Schaffhausen, J. H., Boyle, H. D., Smith, I. F., Parker, I. & Carew, T. J., Jun 30 2010, In : Journal of Neuroscience. 30, 26, p. 8797-8806 10 p.

    Research output: Contribution to journalArticle

    2009

    Temporal Phases of Activity-Dependent Plasticity and Memory Are Mediated by Compartmentalized Routing of MAPK Signaling in Aplysia Sensory Neurons

    Shobe, J. L., Zhao, Y., Stough, S., Ye, X., Hsuan, V., Martin, K. C. & Carew, T. J., Jan 15 2009, In : Neuron. 61, 1, p. 113-125 13 p.

    Research output: Contribution to journalArticle

    2008

    Aplysia synapse associated protein (APSAP): Identification, characterization, and selective interactions with Shaker-type potassium channels

    Reissner, K. J., Boyle, H. D., Ye, X. & Carew, T. J., May 1 2008, In : Journal of Neurochemistry. 105, 3, p. 1006-1018 13 p.

    Research output: Contribution to journalArticle

    Small G proteins exhibit pattern sensitivity in MAPK activation during the induction of memory and synaptic facilitation in Aplysia

    Ye, X., Shobe, J. L., Sharma, S. K., Marina, A. & Carew, T. J., Dec 23 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 51, p. 20511-20516 6 p.

    Research output: Contribution to journalArticle

    2007

    Transient mitogen-activated protein kinase activation is confined to a narrow temporal window required for the induction of two-trial long-term memory in Aplysia

    Philips, G. T., Tzvetkova, E. I. & Carew, T. J., Dec 12 2007, In : Journal of Neuroscience. 27, 50, p. 13701-13705 5 p.

    Research output: Contribution to journalArticle

    2006

    A tropomyosin-related kinase B ligand is required for ERK activation, long-term synaptic facilitation, and long-term memory in Aplysia

    Sharma, S. K., Sherff, C. M., Stough, S., Hsuan, V. & Carew, T. J., Sep 19 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 38, p. 14206-14210 5 p.

    Research output: Contribution to journalArticle

    Latent memory for sensitization in Aplysia

    Philips, G. T., Tzvetkova, E. I., Marinesco, S. & Carew, T. J., Mar 1 2006, In : Learning and Memory. 13, 2, p. 224-229 6 p.

    Research output: Contribution to journalArticle

    Regulation of behavioral and synaptic plasticity by serotonin release within local modulatory fields in the CNS of Aplysia

    Marinesco, S., Wickremasinghe, N. & Carew, T. J., Dec 6 2006, In : Journal of Neuroscience. 26, 49, p. 12682-12693 12 p.

    Research output: Contribution to journalArticle

    2005

    Differential role of inhibition in habituation of two independent afferent pathways to a common motor output

    Bristol, A. S. & Carew, T. J., Jan 1 2005, In : Learning and Memory. 12, 1, p. 52-60 9 p.

    Research output: Contribution to journalArticle

    2004

    Intermediate-Term Memory for Site-Specific Sensitization in Aplysia is Maintained by Persistent Activation of Protein Kinase C

    Sutton, M. A., Bagnall, M. W., Sharma, S. K., Shobe, J. & Carew, T. J., Apr 7 2004, In : Journal of Neuroscience. 24, 14, p. 3600-3609 10 p.

    Research output: Contribution to journalArticle

    Neural Circuit of Tail-Elicited Siphon Withdrawal in Aplysia. I. Differential Lateralization of Sensitization and Dishabituation

    Bristol, A. S., Sutton, M. A. & Carew, T. J., Feb 1 2004, In : Journal of neurophysiology. 91, 2, p. 666-677 12 p.

    Research output: Contribution to journalArticle

    Serotonergic modulation in Aplysia. I. Distributed serotonergic network persistently activated by sensitizing stimuli

    Marinesco, S., Kolkman, K. E. & Carew, T. J., Oct 1 2004, In : Journal of neurophysiology. 92, 4, p. 2468-2486 19 p.

    Research output: Contribution to journalArticle

    Serotonergic modulation in Aplysia. II. Cellular and behavioral consequences of increased serotonergic tone

    Marinesco, S., Wickremasinghe, N., Kolkman, K. E. & Carew, T. J., Oct 1 2004, In : Journal of neurophysiology. 92, 4, p. 2487-2496 10 p.

    Research output: Contribution to journalArticle

    2003

    Activation of a tyrosine kinase-MAPK cascade enhances the induction of long-term synaptic facilitation and long-term memory in Aplysia

    Purcell, A. L., Sharma, S. K., Bagnall, M. W., Sutton, M. A. & Carew, T. J., Feb 6 2003, In : Neuron. 37, 3, p. 473-484 12 p.

    Research output: Contribution to journalArticle

    Differential role of mitogen-activated protein kinase in three distinct phases of memory for sensitization in Aplysia

    Sharma, S. K., Sherff, C. M., Shobe, J., Bagnall, M. W., Sutton, M. A. & Carew, T. J., May 1 2003, In : Journal of Neuroscience. 23, 9, p. 3899-3907 9 p.

    Research output: Contribution to journalArticle

    Open Access
    2002

    Behavioral, cellular, and molecular analysis of memory in Aplysia I: Intermediate-term memory

    Sutton, M. A. & Carew, T. J., Aug 2002, In : Integrative and Comparative Biology. 42, 4, p. 725-735 11 p.

    Research output: Contribution to journalArticle

    Open Access

    Behavioral, cellular, and molecular analysis of memory in aplysia II: Long-term facilitation

    Sherff, C. M. & Carew, T. J., Aug 1 2002, In : Integrative and Comparative Biology. 42, 4, p. 736-742 7 p.

    Research output: Contribution to journalArticle

    Inclusion of phosphatase inhibitors during Western blotting enhances signal detection with phospho-specific antibodies

    Sharma, S. K. & Carew, T. J., Aug 1 2002, In : Analytical Biochemistry. 307, 1, p. 187-189 3 p.

    Research output: Contribution to journalArticle

    Interaction between amount and pattern of training in the induction of intermediate- and long-term memory for sensitization in Aplysia

    Sutton, M. A., Ide, J., Masters, S. E. & Carew, T. J., Apr 15 2002, In : Learning and Memory. 9, 1, p. 29-40 12 p.

    Research output: Contribution to journalArticle

    2001

    Aplysia ror forms clusters on the surface of identified neuroendocrine cells

    McKay, S. E., Hislop, J., Scott, D., Bulloch, A. G. M., Kaczmarek, L. K., Carew, T. J. & Sossin, W. S., Jan 1 2001, In : Molecular and Cellular Neuroscience. 17, 5, p. 821-841 21 p.

    Research output: Contribution to journalArticle

    Combined effects of intrinsic facilitation and modulatory inhibition of identified interneurons in the siphon withdrawal circuitry of Aplysia

    Bristol, A. S., Fischer, T. M. & Carew, T. J., Nov 15 2001, In : Journal of Neuroscience. 21, 22, p. 8990-9000 11 p.

    Research output: Contribution to journalArticle

    Contribution of postsynaptic Ca2+ to the induction of posttetanic potentiation in the neural circuit for siphon withdrawal in Aplysia

    Schaffhausen, J. H., Fischer, T. M. & Carew, T. J., Mar 1 2001, In : Journal of Neuroscience. 21, 5, p. 1739-1749 11 p.

    Research output: Contribution to journalArticle

    Molecular mechanisms underlying a unique intermediate phase of memory in Aplysia

    Sutton, M. A., Masters, S. E., Bagnall, M. W. & Carew, T. J., Jan 1 2001, In : Neuron. 31, 1, p. 143-154 12 p.

    Research output: Contribution to journalArticle

    2000

    Dynamic regulation of the siphon withdrawal reflex of Aplysia californica in response to changes in the ambient tactile environment

    Fischer, T. M., Yuan, J. W. & Carew, T. J., Jan 1 2000, In : Behavioral Neuroscience. 114, 6, p. 1209-1222 14 p.

    Research output: Contribution to journalArticle

    Parallel molecular pathways mediate expression of distinct forms of intermediate-term facilitation at tail sensory-motor synapses in Aplysia

    Sutton, M. A. & Carew, T. J., Jan 1 2000, In : Neuron. 26, 1, p. 219-231 13 p.

    Research output: Contribution to journalArticle

    Open Access
    1999

    Coincident induction of long-term facilitation in Aplysia: Cooperativity between cell bodies and remote synapses

    Sherff, C. M. & Carew, T. J., Sep 17 1999, In : Science. 285, 5435, p. 1911-1914 4 p.

    Research output: Contribution to journalArticle

    Developmental dissociation of serotonin-induced spike broadening and synaptic facilitation in Aplysia sensory neurons

    Stark, L. L. & Carew, T. J., Jan 1 1999, In : Journal of Neuroscience. 19, 1, p. 334-346 13 p.

    Research output: Contribution to journalArticle

    Growth factor modulation of substrate-specific morphological patterns in Aplysia bag cell neurons

    Gruenbaum, L. M. & Carew, T. J., Jan 1 1999, In : Learning and Memory. 6, 3, p. 292-306 15 p.

    Research output: Contribution to journalArticle

    1998

    Differential induction of long-term synaptic facilitation by spaced and massed applications of serotonin at sensory neuron synapses of Aplysia californica

    Mauelshagen, J., Sherff, C. M. & Carew, T. J., Dec 1 1998, In : Learning and Memory. 5, 3, p. 246-256 11 p.

    Research output: Contribution to journalArticle

    Protein kinase C regulates a vesicular class of calcium channels in the bag cell neurons of Aplysia

    White, B. H., Nick, T. A., Carew, T. J. & Kaczmarek, L. K., Nov 1998, In : Journal of neurophysiology. 80, 5, p. 2514-2520 7 p.

    Research output: Contribution to journalArticle