11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range

Arun Manickam; Kae Dyi You; Nicholas Wood; Lei Pei; Yang Liu; Rituraj Singh; Nader Gamini; Davood Shahrjerdi; Robert G. Kuimelis; Arjang Hassibi

doi:10.1109/ISSCC.2019.8662507

11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range

Arun Manickam, Kae Dyi You, Nicholas Wood, Lei Pei, Yang Liu, Rituraj Singh, Nader Gamini, Davood Shahrjerdi, Robert G. Kuimelis, Arjang Hassibi

Electrical and Computer Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].

Original language	English (US)
Title of host publication	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	192-194
Number of pages	3
ISBN (Electronic)	9781538685310
DOIs	https://doi.org/10.1109/ISSCC.2019.8662507
State	Published - Mar 6 2019
Event	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 - San Francisco, United States Duration: Feb 17 2019 → Feb 21 2019

Publication series

Name	Digest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume	2019-February
ISSN (Print)	0193-6530

Conference

Conference	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
Country/Territory	United States
City	San Francisco
Period	2/17/19 → 2/21/19

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

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10.1109/ISSCC.2019.8662507

Cite this

Manickam, A., You, K. D., Wood, N., Pei, L., Liu, Y., Singh, R., Gamini, N., Shahrjerdi, D., Kuimelis, R. G., & Hassibi, A. (2019). 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 (pp. 192-194). Article 8662507 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISSCC.2019.8662507

11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. / Manickam, Arun; You, Kae Dyi; Wood, Nicholas et al.
2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 192-194 8662507 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Manickam, A, You, KD, Wood, N, Pei, L, Liu, Y, Singh, R, Gamini, N, Shahrjerdi, D, Kuimelis, RG & Hassibi, A 2019, 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. in 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019., 8662507, Digest of Technical Papers - IEEE International Solid-State Circuits Conference, vol. 2019-February, Institute of Electrical and Electronics Engineers Inc., pp. 192-194, 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019, San Francisco, United States, 2/17/19. https://doi.org/10.1109/ISSCC.2019.8662507

Manickam A, You KD, Wood N, Pei L, Liu Y, Singh R et al. 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 192-194. 8662507. (Digest of Technical Papers - IEEE International Solid-State Circuits Conference). doi: 10.1109/ISSCC.2019.8662507

Manickam, Arun ; You, Kae Dyi ; Wood, Nicholas et al. / 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 192-194 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference).

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abstract = "Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].",

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AU - Singh, Rituraj

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11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range

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