11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range

Arun Manickam, Kae Dyi You, Nicholas Wood, Lei Pei, Yang Liu, Rituraj Singh, Nader Gamini, Davood Shahrjerdi, Robert G. Kuimelis, Arjang Hassibi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].

Original languageEnglish (US)
Title of host publication2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages192-194
Number of pages3
ISBN (Electronic)9781538685310
DOIs
StatePublished - Mar 6 2019
Event2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 - San Francisco, United States
Duration: Feb 17 2019Feb 21 2019

Publication series

NameDigest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume2019-February
ISSN (Print)0193-6530

Conference

Conference2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
CountryUnited States
CitySan Francisco
Period2/17/192/21/19

Fingerprint

Voltammetry
Biosensors
Pixels
Electrodes
Chemical stability
Electrolytes
Transducers
Thermodynamic stability
Networks (circuits)
Sensors
Costs

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering

Cite this

Manickam, A., You, K. D., Wood, N., Pei, L., Liu, Y., Singh, R., ... Hassibi, A. (2019). 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 (pp. 192-194). [8662507] (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISSCC.2019.8662507

11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. / Manickam, Arun; You, Kae Dyi; Wood, Nicholas; Pei, Lei; Liu, Yang; Singh, Rituraj; Gamini, Nader; Shahrjerdi, Davood; Kuimelis, Robert G.; Hassibi, Arjang.

2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 192-194 8662507 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Manickam, A, You, KD, Wood, N, Pei, L, Liu, Y, Singh, R, Gamini, N, Shahrjerdi, D, Kuimelis, RG & Hassibi, A 2019, 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. in 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019., 8662507, Digest of Technical Papers - IEEE International Solid-State Circuits Conference, vol. 2019-February, Institute of Electrical and Electronics Engineers Inc., pp. 192-194, 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019, San Francisco, United States, 2/17/19. https://doi.org/10.1109/ISSCC.2019.8662507
Manickam A, You KD, Wood N, Pei L, Liu Y, Singh R et al. 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 192-194. 8662507. (Digest of Technical Papers - IEEE International Solid-State Circuits Conference). https://doi.org/10.1109/ISSCC.2019.8662507
Manickam, Arun ; You, Kae Dyi ; Wood, Nicholas ; Pei, Lei ; Liu, Yang ; Singh, Rituraj ; Gamini, Nader ; Shahrjerdi, Davood ; Kuimelis, Robert G. ; Hassibi, Arjang. / 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range. 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 192-194 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference).
@inproceedings{28020f6f4c764413aa8badcf48a40afe,
title = "11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range",
abstract = "Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].",
author = "Arun Manickam and You, {Kae Dyi} and Nicholas Wood and Lei Pei and Yang Liu and Rituraj Singh and Nader Gamini and Davood Shahrjerdi and Kuimelis, {Robert G.} and Arjang Hassibi",
year = "2019",
month = "3",
day = "6",
doi = "10.1109/ISSCC.2019.8662507",
language = "English (US)",
series = "Digest of Technical Papers - IEEE International Solid-State Circuits Conference",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "192--194",
booktitle = "2019 IEEE International Solid-State Circuits Conference, ISSCC 2019",

}

TY - GEN

T1 - 11.2 A CMOS Biosensor Array with 1024 3-Electrode Voltammetry Pixels and 93dB Dynamic Range

AU - Manickam, Arun

AU - You, Kae Dyi

AU - Wood, Nicholas

AU - Pei, Lei

AU - Liu, Yang

AU - Singh, Rituraj

AU - Gamini, Nader

AU - Shahrjerdi, Davood

AU - Kuimelis, Robert G.

AU - Hassibi, Arjang

PY - 2019/3/6

Y1 - 2019/3/6

N2 - Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].

AB - Electro-analytical (E-chem) biosensors offer unique advantages over widely used optical biosensors and can be considered ideal for low-cost, mass-deployable point-of-care (PoC) diagnostic devices [1]. They possess fully electronic and real-time transduction methods and require little or no external instrumentation. Despite these advantages, two fundamental challenges have hampered broad adoption of E-chem biosensors: 1C design and transducer (surface) material suitability. E-chem sensors require both low-noise and high detection dynamic range (DDR) front-end circuits and must also accommodate electrode-electrolyte interfaces with significant PVT variations and temporal drifts [2]-[5]. The absence of CMOS-compatible bio-electronic interfaces with adequate chemical and thermal stability has been another impediment [6].

UR - http://www.scopus.com/inward/record.url?scp=85063444897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85063444897&partnerID=8YFLogxK

U2 - 10.1109/ISSCC.2019.8662507

DO - 10.1109/ISSCC.2019.8662507

M3 - Conference contribution

T3 - Digest of Technical Papers - IEEE International Solid-State Circuits Conference

SP - 192

EP - 194

BT - 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019

PB - Institute of Electrical and Electronics Engineers Inc.

ER -