3 Tesla magnetic resonance imaging of the brain in newborns

John H. Gilmore; Guihua Zhai; Kathy Wilber; J. Keith Smith; Weili Lin; Guido Gerig

doi:10.1016/j.pscychresns.2004.04.004

3 Tesla magnetic resonance imaging of the brain in newborns

John H. Gilmore, Guihua Zhai, Kathy Wilber, J. Keith Smith, Weili Lin, Guido Gerig

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

While it has been hypothesized that brain development is abnormal in schizophrenia and other neurodevelopmental disorders, there have been few attempts to study very early brain development in children. Twenty unsedated healthy newborns underwent 3 Tesla magnetic resonance imaging (MRI), including diffusion tensor imaging (DTI). The left ventricle was significantly larger than the right; females had significantly larger ventricles than males. Fractional anisotropy (FA) increased significantly with gestational age in the genu and splenium of the corpus callosum. It is feasible to study brain development in unsedated newborns using 3 T MRI.

Original language	English (US)
Pages (from-to)	81-85
Number of pages	5
Journal	Psychiatry Research - Neuroimaging
Volume	132
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2004.04.004
State	Published - Nov 15 2004

Keywords

Asymmetry
Diffusion tensor imaging
Lateral ventricles
Neonates
Neurodevelopmental disorders
Schizophrenia

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/j.pscychresns.2004.04.004

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title = "3 Tesla magnetic resonance imaging of the brain in newborns",

abstract = "While it has been hypothesized that brain development is abnormal in schizophrenia and other neurodevelopmental disorders, there have been few attempts to study very early brain development in children. Twenty unsedated healthy newborns underwent 3 Tesla magnetic resonance imaging (MRI), including diffusion tensor imaging (DTI). The left ventricle was significantly larger than the right; females had significantly larger ventricles than males. Fractional anisotropy (FA) increased significantly with gestational age in the genu and splenium of the corpus callosum. It is feasible to study brain development in unsedated newborns using 3 T MRI.",

keywords = "Asymmetry, Diffusion tensor imaging, Lateral ventricles, Neonates, Neurodevelopmental disorders, Schizophrenia",

author = "Gilmore, {John H.} and Guihua Zhai and Kathy Wilber and Smith, {J. Keith} and Weili Lin and Guido Gerig",

note = "Funding Information: This work was supported by NIH Conte Center MH064065, Neurodevelopmental Disorders Research Center HD 03110, the Stanley Medical Research Institute, and the Foundation of Hope. The authors thank Jeffrey Lieberman, MD, Elizabeth Webster, PhD, and Joseph Piven, MD, for their support and helpful discussions. Copyright: Copyright 2012 Elsevier B.V., All rights reserved.",

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AU - Gilmore, John H.

AU - Zhai, Guihua

AU - Wilber, Kathy

AU - Smith, J. Keith

AU - Lin, Weili

AU - Gerig, Guido

N1 - Funding Information: This work was supported by NIH Conte Center MH064065, Neurodevelopmental Disorders Research Center HD 03110, the Stanley Medical Research Institute, and the Foundation of Hope. The authors thank Jeffrey Lieberman, MD, Elizabeth Webster, PhD, and Joseph Piven, MD, for their support and helpful discussions. Copyright: Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2004/11/15

Y1 - 2004/11/15

N2 - While it has been hypothesized that brain development is abnormal in schizophrenia and other neurodevelopmental disorders, there have been few attempts to study very early brain development in children. Twenty unsedated healthy newborns underwent 3 Tesla magnetic resonance imaging (MRI), including diffusion tensor imaging (DTI). The left ventricle was significantly larger than the right; females had significantly larger ventricles than males. Fractional anisotropy (FA) increased significantly with gestational age in the genu and splenium of the corpus callosum. It is feasible to study brain development in unsedated newborns using 3 T MRI.

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KW - Diffusion tensor imaging

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KW - Neonates

KW - Neurodevelopmental disorders

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3 Tesla magnetic resonance imaging of the brain in newborns

Abstract

Keywords

ASJC Scopus subject areas

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