3D DNA crystals and nanotechnology

Paul J. Paukstelis, Nadrian C. Seeman

Research output: Contribution to journalReview articlepeer-review


DNA’s molecular recognition properties have made it one of the most widely used biomacromolecular construction materials. The programmed assembly of DNA oligonucleotides has been used to create complex 2D and 3D self-assembled architectures and to guide the assembly of other molecules. The origins of DNA nanotechnology are rooted in the goal of assembling DNA molecules into designed periodic arrays, i.e., crystals. Here, we highlight several DNA crystal structures, the progress made in designing DNA crystals, and look at the current prospects and future directions of DNA crystals in nanotechnology.

Original languageEnglish (US)
Article number97
Issue number8
StatePublished - Aug 2016


  • Crystal design
  • DNA crystals
  • Nanotechnology

ASJC Scopus subject areas

  • General Chemical Engineering
  • General Materials Science
  • Condensed Matter Physics
  • Inorganic Chemistry


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