3D graph description of the intracerebral vasculature from segmented MRA and tests of accuracy by comparison with x-ray angiograms

Elizabeth Bullitt, Stephen Aylward, Alan Liu, Jeffrey Stone, Suresh K. Mukherji, Chris Coffey, Guido Gerig, Stephen M. Pizer

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    This paper describes largely automated methods of creating connected, 3D vascular trees from individual vessels segmented from magnetic resonance angiograms. Vessel segmentation is initiated by usersupplied seed points, with automatic calculation of vessel skeletons as image intensity ridges and automatic estimation of vessel widths via medialness calculations. The tree-creation process employs a variant of the minimum spanning tree algorithm and evaluates image intensities at each proposed connection point. We evaluate the accuracy of nodal connections by registering a 3D vascular tree with 4 digital subtraction angiograms (DSAs) obtained from the same patient, and by asking two neuroradiologists to evaluate each nodal connection on each DSA view. No connection was judged incorrect. The approach permits new, clinically useful visualizations of the intracerebral vasculature.

    Original languageEnglish (US)
    Title of host publicationInformation Processing in Medical Imaging - 16th InternationalConference, IPMI 1999, Proceedings
    EditorsAttila Kuba, Martin Samal, Andrew Todd-Pokropek
    PublisherSpringer Verlag
    Pages308-321
    Number of pages14
    ISBN (Print)3540661670, 9783540661672
    DOIs
    StatePublished - Jan 1 1999
    Event16th International conference on Information Processing in Medical Imaging, IPMI 1999 - Visegrad, Hungary
    Duration: Jun 28 1999Jul 2 1999

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume1613
    ISSN (Print)0302-9743
    ISSN (Electronic)1611-3349

    Other

    Other16th International conference on Information Processing in Medical Imaging, IPMI 1999
    CountryHungary
    CityVisegrad
    Period6/28/997/2/99

    ASJC Scopus subject areas

    • Theoretical Computer Science
    • Computer Science(all)

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  • Cite this

    Bullitt, E., Aylward, S., Liu, A., Stone, J., Mukherji, S. K., Coffey, C., Gerig, G., & Pizer, S. M. (1999). 3D graph description of the intracerebral vasculature from segmented MRA and tests of accuracy by comparison with x-ray angiograms. In A. Kuba, M. Samal, & A. Todd-Pokropek (Eds.), Information Processing in Medical Imaging - 16th InternationalConference, IPMI 1999, Proceedings (pp. 308-321). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 1613). Springer Verlag. https://doi.org/10.1007/3-540-48714-x_23