3D-Printed Dual-Color Optogenetic Neural Stimulator

Keonghwan Oh; Sohmyung Ha

doi:10.1109/LPT.2023.3314060

3D-Printed Dual-Color Optogenetic Neural Stimulator

Research output: Contribution to journal › Article › peer-review

Abstract

In this letter, we present an optical neural stimulator that utilizes a 3D-printed substrate integrated with conductive wires for electrical connections and micro light-emitting diodes (μ LEDs) for optogenetic stimulation. The proposed device includes two different color LEDs for excitation and inhibition of the targeted neurons on the single optogenetic electrode (optrode). The proposed device is unique in that it is built mainly with 3D-printed custom-made components without the need for microfabrication techniques, allowing for the easy design and manufacture of small, complex shapes without the use of clean-room facilities. The total thickness of the device is just 85μm, generating enough light intensity to excite and inhibit the neurons. The measured electrical, optical, and thermal properties of the device validate the device's characteristics and functionality.

Original language	English (US)
Pages (from-to)	401-404
Number of pages	4
Journal	IEEE Photonics Technology Letters
Volume	36
Issue number	6
DOIs	https://doi.org/10.1109/LPT.2023.3314060
State	Published - Mar 15 2024

Keywords

3D-printing neural probe
Optogenetics
implantable devices
optical neural modulation
optoelectronics device

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Electrical and Electronic Engineering

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10.1109/LPT.2023.3314060

Cite this

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title = "3D-Printed Dual-Color Optogenetic Neural Stimulator",

abstract = "In this letter, we present an optical neural stimulator that utilizes a 3D-printed substrate integrated with conductive wires for electrical connections and micro light-emitting diodes (μ LEDs) for optogenetic stimulation. The proposed device includes two different color LEDs for excitation and inhibition of the targeted neurons on the single optogenetic electrode (optrode). The proposed device is unique in that it is built mainly with 3D-printed custom-made components without the need for microfabrication techniques, allowing for the easy design and manufacture of small, complex shapes without the use of clean-room facilities. The total thickness of the device is just 85μm, generating enough light intensity to excite and inhibit the neurons. The measured electrical, optical, and thermal properties of the device validate the device's characteristics and functionality.",

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3D-Printed Dual-Color Optogenetic Neural Stimulator

Abstract

Keywords

ASJC Scopus subject areas

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