Abstract
A synthetic scaffold that mimics a peptide β-strand has been designed and synthesised based on a 1,3-phenyl-linked hydantoin oligomer. The conformational preferences of this oligomer were investigated using molecular modelling and solution NMR experiments and suggest a planar conformation that accurately mimics the i, i + 2 and i + 4 residues of a peptide β-strand.
Original language | English (US) |
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Pages (from-to) | 3709-3711 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 31 |
DOIs | |
State | Published - Mar 19 2012 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry