A Case for Distributed Control of Local Stem Cell Behavior in Plants

Ramin Rahni; Idan Efroni; Kenneth D. Birnbaum

doi:10.1016/j.devcel.2016.08.015

A Case for Distributed Control of Local Stem Cell Behavior in Plants

Ramin Rahni, Idan Efroni, Kenneth D. Birnbaum

Biology and Genomics

Research output: Contribution to journal › Review article › peer-review

Abstract

The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.

Original language	English (US)
Pages (from-to)	635-642
Number of pages	8
Journal	Developmental Cell
Volume	38
Issue number	6
DOIs	https://doi.org/10.1016/j.devcel.2016.08.015
State	Published - Sep 26 2016

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

Access to Document

10.1016/j.devcel.2016.08.015

Cite this

@article{cd84635992c642d087bee409a46e6a72,

title = "A Case for Distributed Control of Local Stem Cell Behavior in Plants",

abstract = "The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.",

author = "Ramin Rahni and Idan Efroni and Birnbaum, {Kenneth D.}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier Inc.",

year = "2016",

month = sep,

day = "26",

doi = "10.1016/j.devcel.2016.08.015",

language = "English (US)",

volume = "38",

pages = "635--642",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "6",

}

TY - JOUR

T1 - A Case for Distributed Control of Local Stem Cell Behavior in Plants

AU - Rahni, Ramin

AU - Efroni, Idan

AU - Birnbaum, Kenneth D.

PY - 2016/9/26

Y1 - 2016/9/26

N2 - The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.

AB - The root meristem has a centrally located group of mitotically quiescent cells, to which current models assign a stem cell organizer function. However, evidence is emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges from the lack of cell displacement at the border of opposing differentiation gradients. We term this a “stagnation” model due to its reliance on passive mechanics. The position of stem cells is established by two opposing axes that reciprocally control each other's differentiation. Such broad tissue organization programs would allow plants, like some animal systems, to rapidly reconstitute stem cells from non-stem-cell tissues.

UR - http://www.scopus.com/inward/record.url?scp=84991810107&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991810107&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2016.08.015

DO - 10.1016/j.devcel.2016.08.015

M3 - Review article

C2 - 27676436

AN - SCOPUS:84991810107

SN - 1534-5807

VL - 38

SP - 635

EP - 642

JO - Developmental Cell

JF - Developmental Cell

IS - 6

ER -

A Case for Distributed Control of Local Stem Cell Behavior in Plants

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this