A clinical update: Nonceliac gluten sensitivity-is it really the gluten?

Bernadette Capili, Michelle Chang, Joyce K. Anastasi

Research output: Contribution to journalArticlepeer-review


Gluten-free diets are increasing in popularity among consumers and fueling a global market of gluten-free products. A gluten-free diet is the only treatment for celiac disease (CD). However, many patients are self-reporting and suspecting "gluten sensitivity" after gastrointestinal symptoms, such as bloating, abdominal pain, or diarrhea, resolve on a gluten-free diet without formal evaluation testing for food allergies or CD. The terms related to gluten and/or wheat intolerance, nonceliac gluten sensitivity or wheat sensitivity, CD, and wheat allergy can be confusing. These forms of intolerance combined affect approximately 10% of the United States population. In this article we clarify the range of gluten and/or wheat disorders, clinical features, diagnosis, and management.

Original languageEnglish (US)
Pages (from-to)666-673
Number of pages8
JournalJournal for Nurse Practitioners
Issue number9
StatePublished - Oct 1 2014


  • Celiac disease
  • Gluten
  • Nonceliac gluten sensitivity
  • Wheat allergy
  • Wheat sensitivity

ASJC Scopus subject areas

  • Advanced and Specialized Nursing


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