A conceptual framework for adaptive preventive interventions

Linda M. Collins, Susan A. Murphy, Karen L. Bierman

Research output: Contribution to journalReview articlepeer-review


Recently, adaptive interventions have emerged as a new perspective on prevention and treatment. Adaptive interventions resemble clinical practice in that different dosages of certain prevention or treatment components are assigned to different individuals, and/or within individuals across time, with dosage varying in response to the intervention needs of individuals. To determine intervention need and thus assign dosage, adaptive interventions use prespecified decision rules based on each participant's values on key characteristics, called tailoring variables. In this paper, we offer a conceptual framework for adaptive interventions, discuss principles underlying the design and evaluation of such interventions, and review some areas where additional research is needed.

Original languageEnglish (US)
Pages (from-to)185-196
Number of pages12
JournalPrevention Science
Issue number3
StatePublished - Sep 2004


  • adaptive interventions
  • prevention
  • research design

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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