TY - JOUR
T1 - A cornucopia of research resources for the fourth rodent malaria parasite species
AU - Carlton, Jane M.
N1 - Funding Information:
This commentary is dedicated to all the small animal and mosquito colony technicians, and especially to Mrs. Margaret Mooney at the University of Edinburgh, who tirelessly maintained these resources over decades, making complex malaria experiments possible.
Publisher Copyright:
© 2021, The Author(s).
PY - 2021/12
Y1 - 2021/12
N2 - The study of human malaria caused by species of Plasmodium has undoubtedly been enriched by the use of model systems, such as the rodent malaria parasites originally isolated from African thicket rats. A significant gap in the arsenal of resources of the species that make up the rodent malaria parasites has been the lack of any such tools for the fourth of the species, Plasmodium vinckei. This has recently been rectified by Abhinay Ramaprasad and colleagues, whose pivotal paper published in BMC Biology describes a cornucopia of new P. vinckei ‘omics datasets, mosquito transmission experiments, transfection protocols, and virulence phenotypes, to propel this species firmly into the twenty-first century.
AB - The study of human malaria caused by species of Plasmodium has undoubtedly been enriched by the use of model systems, such as the rodent malaria parasites originally isolated from African thicket rats. A significant gap in the arsenal of resources of the species that make up the rodent malaria parasites has been the lack of any such tools for the fourth of the species, Plasmodium vinckei. This has recently been rectified by Abhinay Ramaprasad and colleagues, whose pivotal paper published in BMC Biology describes a cornucopia of new P. vinckei ‘omics datasets, mosquito transmission experiments, transfection protocols, and virulence phenotypes, to propel this species firmly into the twenty-first century.
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U2 - 10.1186/s12915-021-01019-y
DO - 10.1186/s12915-021-01019-y
M3 - Comment/debate
C2 - 33888109
AN - SCOPUS:85104695222
SN - 1741-7007
VL - 19
JO - BMC Biology
JF - BMC Biology
IS - 1
M1 - 82
ER -