A Descent into the Nuage: The Maelstrom of Transposon Control

Kathryn A. O'Donnell, Kathleen H. Burns, Jef D. Boeke

    Research output: Contribution to journalShort survey

    Abstract

    In this issue of Developmental Cell, Soper et al. (2008) report that the mammalian MAELSTROM (MAEL) protein is critical for transposon silencing in the male germline. Loss of MAEL is associated with meiotic failure and DNA damage, suggesting that efficient transposable element restraining mechanisms must be in place for the preservation of germline integrity.

    Original languageEnglish (US)
    Pages (from-to)179-181
    Number of pages3
    JournalDevelopmental Cell
    Volume15
    Issue number2
    DOIs
    StatePublished - Aug 12 2008

    ASJC Scopus subject areas

    • Molecular Biology
    • Biochemistry, Genetics and Molecular Biology(all)
    • Developmental Biology
    • Cell Biology

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