A dynamic model of learning in the septo-hippocampal system

Bas Rokers; Catherine E. Myers; Mark A. Gluck

doi:10.1016/S0925-2312(00)00205-8

A dynamic model of learning in the septo-hippocampal system

Bas Rokers, Catherine E. Myers, Mark A. Gluck

Psychology

Research output: Contribution to journal › Conference article › peer-review

Abstract

Gluck and Myers (Hippocampus 3 (1993) 491-516) modeled the hippocampus as an auto-encoder; Myers et al. (Neurobiol. Learning Memory 66 (1996) 51-66) argued that the cholinergic input from medial septum modulates learning rate in this auto-encoder. Neurophysiological evidence suggests the hippocampus self-regulates septal acetylcholine release in response to novel stimuli (Hasselmo and Schnell, J. Neurosci. 14 (1994) 3898-3914). We have extended our earlier model of septohippocampal modulation to include such a feedback loop. The resulting dynamic model learns faster and better than the earlier version on phenomena such as blocking and shift reversal. It can also be applied to data regarding the effects of the anticholinergic drug scopolamine. (C) 2000 Elsevier Science B.V. All rights reserved.

Original language	English (US)
Pages (from-to)	501-507
Number of pages	7
Journal	Neurocomputing
Volume	32-33
DOIs	https://doi.org/10.1016/S0925-2312(00)00205-8
State	Published - Jun 2000
Event	The 8th Annual Computational Neuroscience Meeting (CNS'99) - Pittsburgh, PA, USA Duration: Jul 18 1999 → Jul 22 1999

Keywords

Acetylcholine
Hippocampus
Model
Neuromodulation
Septum

ASJC Scopus subject areas

Computer Science Applications
Cognitive Neuroscience
Artificial Intelligence

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10.1016/S0925-2312(00)00205-8

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title = "A dynamic model of learning in the septo-hippocampal system",

abstract = "Gluck and Myers (Hippocampus 3 (1993) 491-516) modeled the hippocampus as an auto-encoder; Myers et al. (Neurobiol. Learning Memory 66 (1996) 51-66) argued that the cholinergic input from medial septum modulates learning rate in this auto-encoder. Neurophysiological evidence suggests the hippocampus self-regulates septal acetylcholine release in response to novel stimuli (Hasselmo and Schnell, J. Neurosci. 14 (1994) 3898-3914). We have extended our earlier model of septohippocampal modulation to include such a feedback loop. The resulting dynamic model learns faster and better than the earlier version on phenomena such as blocking and shift reversal. It can also be applied to data regarding the effects of the anticholinergic drug scopolamine. (C) 2000 Elsevier Science B.V. All rights reserved.",

keywords = "Acetylcholine, Hippocampus, Model, Neuromodulation, Septum",

author = "Bas Rokers and Myers, {Catherine E.} and Gluck, {Mark A.}",

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journal = "Neurocomputing",

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note = "The 8th Annual Computational Neuroscience Meeting (CNS'99) ; Conference date: 18-07-1999 Through 22-07-1999",

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T1 - A dynamic model of learning in the septo-hippocampal system

AU - Rokers, Bas

AU - Myers, Catherine E.

AU - Gluck, Mark A.

PY - 2000/6

Y1 - 2000/6

N2 - Gluck and Myers (Hippocampus 3 (1993) 491-516) modeled the hippocampus as an auto-encoder; Myers et al. (Neurobiol. Learning Memory 66 (1996) 51-66) argued that the cholinergic input from medial septum modulates learning rate in this auto-encoder. Neurophysiological evidence suggests the hippocampus self-regulates septal acetylcholine release in response to novel stimuli (Hasselmo and Schnell, J. Neurosci. 14 (1994) 3898-3914). We have extended our earlier model of septohippocampal modulation to include such a feedback loop. The resulting dynamic model learns faster and better than the earlier version on phenomena such as blocking and shift reversal. It can also be applied to data regarding the effects of the anticholinergic drug scopolamine. (C) 2000 Elsevier Science B.V. All rights reserved.

AB - Gluck and Myers (Hippocampus 3 (1993) 491-516) modeled the hippocampus as an auto-encoder; Myers et al. (Neurobiol. Learning Memory 66 (1996) 51-66) argued that the cholinergic input from medial septum modulates learning rate in this auto-encoder. Neurophysiological evidence suggests the hippocampus self-regulates septal acetylcholine release in response to novel stimuli (Hasselmo and Schnell, J. Neurosci. 14 (1994) 3898-3914). We have extended our earlier model of septohippocampal modulation to include such a feedback loop. The resulting dynamic model learns faster and better than the earlier version on phenomena such as blocking and shift reversal. It can also be applied to data regarding the effects of the anticholinergic drug scopolamine. (C) 2000 Elsevier Science B.V. All rights reserved.

KW - Acetylcholine

KW - Hippocampus

KW - Model

KW - Neuromodulation

KW - Septum

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T2 - The 8th Annual Computational Neuroscience Meeting (CNS'99)

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ER -

A dynamic model of learning in the septo-hippocampal system

Abstract

Keywords

ASJC Scopus subject areas

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