A foot in the door: How the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis

Xavier H. Jaglin; Gord Fishell

doi:10.1016/j.stem.2013.09.013

A foot in the door: How the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis

Xavier H. Jaglin, Gord Fishell

Center for Genomics and Systems Biology

Research output: Contribution to journal › Short survey › peer-review

Abstract

Transcription factors and chromatin modifiers are known to contribute to cell specification. However, whether and how they jointly act is poorly understood. In this issue of Cell Stem Cell, Ninkovic et al. show that Pax6 and Brg1 cooperate to modulate gene expression in order to direct neurogenic fate in the olfactory bulb.

Original language	English (US)
Pages (from-to)	373-374
Number of pages	2
Journal	Cell Stem Cell
Volume	13
Issue number	4
DOIs	https://doi.org/10.1016/j.stem.2013.09.013
State	Published - Oct 3 2013

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2013.09.013

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abstract = "Transcription factors and chromatin modifiers are known to contribute to cell specification. However, whether and how they jointly act is poorly understood. In this issue of Cell Stem Cell, Ninkovic et al. show that Pax6 and Brg1 cooperate to modulate gene expression in order to direct neurogenic fate in the olfactory bulb.",

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AB - Transcription factors and chromatin modifiers are known to contribute to cell specification. However, whether and how they jointly act is poorly understood. In this issue of Cell Stem Cell, Ninkovic et al. show that Pax6 and Brg1 cooperate to modulate gene expression in order to direct neurogenic fate in the olfactory bulb.

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A foot in the door: How the chromatin modifier Brg1 and Pax6 jointly potentiate adult neurogenesis

Abstract

ASJC Scopus subject areas

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