A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong, Molly Flexman, Jennifer W. Hoi, Lauren Geller, Maria Garzon, Hyun K. Kim, Andreas H. Hielscher

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.

Original languageEnglish (US)
Title of host publicationOptical Tomography and Spectroscopy of Tissue X
DOIs
StatePublished - 2013
EventOptical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States
Duration: Feb 3 2013Feb 6 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8578
ISSN (Print)1605-7422

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue X
Country/TerritoryUnited States
CitySan Francisco, CA
Period2/3/132/6/13

Keywords

  • diffuse optical spectroscopy
  • handheld
  • hemangiomas
  • wireless

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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