A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong, Molly Flexman, Jennifer W. Hoi, Lauren Geller, Maria Garzon, Hyun K. Kim, Andreas H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.

    Original languageEnglish (US)
    Title of host publicationOptical Tomography and Spectroscopy of Tissue X
    DOIs
    StatePublished - 2013
    EventOptical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States
    Duration: Feb 3 2013Feb 6 2013

    Publication series

    NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume8578
    ISSN (Print)1605-7422

    Conference

    ConferenceOptical Tomography and Spectroscopy of Tissue X
    CountryUnited States
    CitySan Francisco, CA
    Period2/3/132/6/13

    Keywords

    • diffuse optical spectroscopy
    • handheld
    • hemangiomas
    • wireless

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

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