A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong; Molly Flexman; Jennifer W. Hoi; Lauren Geller; Maria Garzon; Hyun K. Kim; Andreas H. Hielscher

doi:10.1117/12.2004717

A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Christopher J. Fong, Molly Flexman, Jennifer W. Hoi, Lauren Geller, Maria Garzon, Hyun K. Kim, Andreas H. Hielscher

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.

Original language	English (US)
Title of host publication	Optical Tomography and Spectroscopy of Tissue X
DOIs	https://doi.org/10.1117/12.2004717
State	Published - 2013
Event	Optical Tomography and Spectroscopy of Tissue X - San Francisco, CA, United States Duration: Feb 3 2013 → Feb 6 2013

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8578
ISSN (Print)	1605-7422

Conference

Conference	Optical Tomography and Spectroscopy of Tissue X
Country/Territory	United States
City	San Francisco, CA
Period	2/3/13 → 2/6/13

Keywords

diffuse optical spectroscopy
handheld
hemangiomas
wireless

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

Access to Document

10.1117/12.2004717

Cite this

Fong, C. J., Flexman, M., Hoi, J. W., Geller, L., Garzon, M., Kim, H. K., & Hielscher, A. H. (2013). A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas. In Optical Tomography and Spectroscopy of Tissue X Article 85780R (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8578). https://doi.org/10.1117/12.2004717

A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas. / Fong, Christopher J.; Flexman, Molly; Hoi, Jennifer W. et al.
Optical Tomography and Spectroscopy of Tissue X. 2013. 85780R (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8578).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fong, CJ, Flexman, M, Hoi, JW, Geller, L, Garzon, M, Kim, HK & Hielscher, AH 2013, A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas. in Optical Tomography and Spectroscopy of Tissue X., 85780R, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8578, Optical Tomography and Spectroscopy of Tissue X, San Francisco, CA, United States, 2/3/13. https://doi.org/10.1117/12.2004717

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abstract = "Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.",

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AB - Infantile hemangiomas (IH) are common vascular growths that occur in 5-10% of neonates and have the potential to cause disfiguring and even life-threatening complications. With no objective tool to monitor IH, a handheld wireless device (HWD) that uses diffuse optical spectroscopy has been developed for use in assessment of IH by measurements in absolute oxygenated and deoxygenated hemoglobin concentration as well as scattering in tissue. Reconstructions of these variables can be computed using a multispectral evolution algorithm. We validated the new system by experimental studies using phantom experiments and a clinical study is under way to assess the utility of DOI for IH.

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A handheld wireless device for diffuse optical spectroscopic assessment of infantile hemangiomas

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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