A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection

S. Holler, V. R. Dantham, V. Kolchenko, Z. Wan, S. Arnold

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our hybrid plasmonic whispering gallery mode biosensor has recently demonstrated detection and characterization of the smallest known RNA virus. A gold nanoparticle affixed to the resonator surface acts like a nanoscopic antenna, enhancing locally the electric field within the cavity mode. When a target analyte binds with this nanoscopic antenna the result is an enhanced response (spectral shift) of the resonator system to the binding event. We have observed shift enhancements ∼70× over the response of the bare resonator, thereby permitting the detection and characterization of all known viral particles and even some large protein molecules.

Original languageEnglish (US)
Title of host publicationFiber Optic Sensors and Applications X
DOIs
StatePublished - 2013
EventFiber Optic Sensors and Applications X - Baltimore, MD, United States
Duration: May 2 2013May 3 2013

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8722
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Other

OtherFiber Optic Sensors and Applications X
CountryUnited States
CityBaltimore, MD
Period5/2/135/3/13

Keywords

  • Biosensing
  • Microcavity
  • Photonics
  • Plasmonics
  • Reactive sensing principle
  • Resonance
  • Virus
  • Whispering gallery mode

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint Dive into the research topics of 'A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection'. Together they form a unique fingerprint.

  • Cite this

    Holler, S., Dantham, V. R., Kolchenko, V., Wan, Z., & Arnold, S. (2013). A hybrid plasmonic whispering gallery mode sensor for single bionanoparticle detection. In Fiber Optic Sensors and Applications X [87220T] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 8722). https://doi.org/10.1117/12.2015506