A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau

Fahu Chen, Frido Welker, Chuan Chou Shen, Shara E. Bailey, Inga Bergmann, Simon Davis, Huan Xia, Hui Wang, Roman Fischer, Sarah E. Freidline, Tsai Luen Yu, Matthew M. Skinner, Stefanie Stelzer, Guangrong Dong, Qiaomei Fu, Guanghui Dong, Jian Wang, Dongju Zhang, Jean Jacques Hublin

    Research output: Contribution to journalArticle

    Abstract

    Denisovans are members of a hominin group who are currently only known directly from fragmentary fossils, the genomes of which have been studied from a single site, Denisova Cave1–3 in Siberia. They are also known indirectly from their genetic legacy through gene flow into several low-altitude East Asian populations4,5 and high-altitude modern Tibetans6. The lack of morphologically informative Denisovan fossils hinders our ability to connect geographically and temporally dispersed fossil hominins from Asia and to understand in a coherent manner their relation to recent Asian populations. This includes understanding the genetic adaptation of humans to the high-altitude Tibetan Plateau7,8, which was inherited from the Denisovans. Here we report a Denisovan mandible, identified by ancient protein analysis9,10, found on the Tibetan Plateau in Baishiya Karst Cave, Xiahe, Gansu, China. We determine the mandible to be at least 160 thousand years old through U-series dating of an adhering carbonate matrix. The Xiahe specimen provides direct evidence of the Denisovans outside the Altai Mountains and its analysis unique insights into Denisovan mandibular and dental morphology. Our results indicate that archaic hominins occupied the Tibetan Plateau in the Middle Pleistocene epoch and successfully adapted to high-altitude hypoxic environments long before the regional arrival of modern Homo sapiens.

    Original languageEnglish (US)
    Pages (from-to)409-412
    Number of pages4
    JournalNature
    Volume569
    Issue number7756
    DOIs
    StatePublished - May 16 2019

    ASJC Scopus subject areas

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    Chen, F., Welker, F., Shen, C. C., Bailey, S. E., Bergmann, I., Davis, S., Xia, H., Wang, H., Fischer, R., Freidline, S. E., Yu, T. L., Skinner, M. M., Stelzer, S., Dong, G., Fu, Q., Dong, G., Wang, J., Zhang, D., & Hublin, J. J. (2019). A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau. Nature, 569(7756), 409-412. https://doi.org/10.1038/s41586-019-1139-x