A model of cell sorting

D. Sulsky; S. Childress; J. K. Percus

doi:10.1016/0022-5193(84)90031-6

A model of cell sorting

D. Sulsky, S. Childress, J. K. Percus

Mathematics

Research output: Contribution to journal › Article › peer-review

Abstract

Voronoi polygons are introduced as a suitable representation for a two-dimensional cell sheet. These polygons are defined in terms of a finite number of points, making numerical simulations tractable and yet allowing cells to change neighbors and their shape in response to deforming forces without leaving gaps in the tissue. Using this geometry and an extension of the equilibrium theory proposed by Steinberg to drive the motion, simulations of rounding of uneven tissue and engulfment of two intact tissues are carried out.

Original language	English (US)
Pages (from-to)	275-301
Number of pages	27
Journal	Journal of Theoretical Biology
Volume	106
Issue number	3
DOIs	https://doi.org/10.1016/0022-5193(84)90031-6
State	Published - Feb 7 1984

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

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10.1016/0022-5193(84)90031-6

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AU - Percus, J. K.

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A model of cell sorting

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ASJC Scopus subject areas

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