A Pilot Mixed-Methods Study of Malignant Pleural Mesothelioma Symptoms

Suzanne L. Walker, Victoria Vaughan Dickson, Pamela Z. Cacchione

Research output: Contribution to journalArticlepeer-review


OBJECTIVES: To describe symptoms of malignant pleural mesothelioma (MPM), a rare cancer associated with a poor prognosis and significant symptoms, via a pilot mixed-methods study, because it is unclear whether MPM symptom assessment tools accurately characterize these symptoms. SAMPLE & SETTING: Participants with MPM were recruited from a large northeastern U.S. academic medical center with an interprofessional MPM program. METHODS & VARIABLES: A mixed-methods pilot approach was employed using the Lung Cancer Symptom Scale for Mesothelioma (LCSS-Meso) to quantitatively describe MPM symptoms and semistructured interviews to qualitatively capture these symptoms. RESULTS: Seven participants with MPM completed the LCSS-Meso and qualitative interviews. The five symptoms evaluated by the LCSS-Meso were confirmed as symptoms of MPM in participant interviews. However, the presence and severity of some symptoms were either under-or overestimated by the scale. Two additional symptoms, distress and sleep disturbance, also emerged from the qualitative interviews. IMPLICATIONS FOR NURSING: Nurses caring for people with MPM should have a thorough understanding of common symptoms, but they must also explore additional symptoms that are meaningful to each patient.

Original languageEnglish (US)
Pages (from-to)615-623
Number of pages9
JournalOncology nursing forum
Issue number6
StatePublished - Nov 2022


  • LCSS-Meso
  • malignant pleural mesothelioma
  • mixed methods
  • symptoms

ASJC Scopus subject areas

  • Oncology(nursing)


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