A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

Michael Holbach, Xiaolai Zheng, Caroline Burd, Christopher W. Jones, Marcus Weck

Research output: Contribution to journalArticlepeer-review

Abstract

A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.

Original languageEnglish (US)
Pages (from-to)2903-2906
Number of pages4
JournalJournal of Organic Chemistry
Volume71
Issue number7
DOIs
StatePublished - Apr 1 2006

ASJC Scopus subject areas

  • Organic Chemistry

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