A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

Michael Holbach; Xiaolai Zheng; Caroline Burd; Christopher W. Jones; Marcus Weck

doi:10.1021/jo052614y

A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

Michael Holbach, Xiaolai Zheng, Caroline Burd, Christopher W. Jones, Marcus Weck

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.

Original language	English (US)
Pages (from-to)	2903-2906
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	71
Issue number	7
DOIs	https://doi.org/10.1021/jo052614y
State	Published - Apr 1 2006

ASJC Scopus subject areas

Organic Chemistry

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10.1021/jo052614y

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title = "A practical one-pot synthesis of enantiopure unsymmetrical salen ligands",

abstract = "A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.",

author = "Michael Holbach and Xiaolai Zheng and Caroline Burd and Jones, {Christopher W.} and Marcus Weck",

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AU - Jones, Christopher W.

AU - Weck, Marcus

PY - 2006/4/1

Y1 - 2006/4/1

N2 - A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.

AB - A practical, one-pot synthesis of enantiopure unsymmetrical salen ligands is described, using a 1:1:1 molar ratio of a chiral diamine and two different salicylaldehydes. The new synthetic protocol can be readily performed in good yields (60-85%) on a multigram scale with good tolerance toward various functional groups.

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A practical one-pot synthesis of enantiopure unsymmetrical salen ligands

Abstract

ASJC Scopus subject areas

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