Mandibles of 4-month-old and 14- to 18-month-old freshly slaughtered steers were utilized to quantitate the immunoglobulin content of the dental pulp and gingiva. Using a single radial immunodiffusion technique, IgG was found in lower concentrations in the pulp and gingiva than in sera. IgG was used as a monitor of relative immunologic activity. When mandibles of older steers were examined, there was an increase in gingival concentrations of IgG and a decrease in pulpal concentrations of IgG. The steer provided an animal model system for the study of immunoglobulin levels in normal dental pulp and gingiva.
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