A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids

Michael Pangerl, Ignaz Höhlein, Dirk Trauner

Research output: Contribution to journalArticlepeer-review

Abstract

A diastereoselective Fráter-Seebach-type alkylation provides access to a highly functionalized pyrrolizidine, which could serve as a key building block for the total synthesis of ÂDaphniphyllum alkaloids, such as oldhamine A.

Original languageEnglish (US)
Article numberST-2013-B1030-L
Pages (from-to)741-745
Number of pages5
JournalSynlett
Volume25
Issue number5
DOIs
StatePublished - Mar 2014

Keywords

  • Daphniphyllum alkaloids
  • asymmetric synthesis
  • heteroÂcycles
  • oldhamine A
  • pyrrolizidines

ASJC Scopus subject areas

  • Organic Chemistry

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