A supramolecular approach for preparation of size-controlled nanoparticles

Hao Wang; Shutao Wang; Helen Su; Kuan Ju Chen; Amanda Lee Armijo; Wei Yu Lin; Yanju Wang; Jing Sun; Ken Ichiro Kamei; Johannes Czernin; Caius G. Radu; Hsian Rong Tseng

doi:10.1002/anie.200900063

A supramolecular approach for preparation of size-controlled nanoparticles

Hao Wang, Shutao Wang, Helen Su, Kuan Ju Chen, Amanda Lee Armijo, Wei Yu Lin, Yanju Wang, Jing Sun, Ken Ichiro Kamei, Johannes Czernin, Caius G. Radu, Hsian Rong Tseng

Biology

Research output: Contribution to journal › Article › peer-review

Abstract

A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture).

Original language	English (US)
Pages (from-to)	4344-4348
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	24
DOIs	https://doi.org/10.1002/anie.200900063
State	Published - Jun 2 2009

Keywords

Adamantanes
Biodistribution
Cyclodextrins
Nanoparticles
Positron emission tomography

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.200900063

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title = "A supramolecular approach for preparation of size-controlled nanoparticles",

abstract = "A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture).",

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AU - Wang, Hao

AU - Wang, Shutao

AU - Su, Helen

AU - Chen, Kuan Ju

AU - Armijo, Amanda Lee

AU - Lin, Wei Yu

AU - Wang, Yanju

AU - Sun, Jing

AU - Kamei, Ken Ichiro

AU - Czernin, Johannes

AU - Radu, Caius G.

AU - Tseng, Hsian Rong

PY - 2009/6/2

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AB - A supramolecular approach has been developed for the preparation of supramolecular nanoparticles (SNPs) with variable sizes (30-450 nm) from three different molecular building blocks using a cyclodextrin/adamantane recognition system. Positron emission tomography (PET) was employed to study the biodistribution and lymph node drainage of the SNPs in mice. The sizes of the SNPs affect their in vivo characteristics (see picture).

KW - Adamantanes

KW - Biodistribution

KW - Cyclodextrins

KW - Nanoparticles

KW - Positron emission tomography

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A supramolecular approach for preparation of size-controlled nanoparticles

Abstract

Keywords

ASJC Scopus subject areas

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