A synthetic analogue of the carboxylate-binding pocket of vancomycin

Michael J. Mann; Nalin Pant; Andrew D. Hamilton

doi:10.1039/C39860000158

A synthetic analogue of the carboxylate-binding pocket of vancomycin

Michael J. Mann, Nalin Pant, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A synthetic analogue of the right-hand ring of vancomycin, the region in the antibiotic which contains the pocket for binding to the terminal carboxylate of D-Ala-D-Ala containing peptides, has been prepared and shows structural and spectroscopic similarity to the natural molecule.

Original language	English (US)
Pages (from-to)	158-160
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	2
DOIs	https://doi.org/10.1039/C39860000158
State	Published - 1986

ASJC Scopus subject areas

Molecular Medicine

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title = "A synthetic analogue of the carboxylate-binding pocket of vancomycin",

abstract = "A synthetic analogue of the right-hand ring of vancomycin, the region in the antibiotic which contains the pocket for binding to the terminal carboxylate of D-Ala-D-Ala containing peptides, has been prepared and shows structural and spectroscopic similarity to the natural molecule.",

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year = "1986",

doi = "10.1039/C39860000158",

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AU - Pant, Nalin

AU - Hamilton, Andrew D.

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A synthetic analogue of the carboxylate-binding pocket of vancomycin

Abstract

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