Teoreticheskaia model' upakovki DNK v golovke faga.

I. S. Gabashvili; A. I. Grosberg; D. V. Kuznetsov; G. M. Mrevlishvili

Teoreticheskaia model' upakovki DNK v golovke faga.

Translated title of the contribution: A theoretical model of DNA packaging in the phage head

I. S. Gabashvili, A. I. Grosberg, D. V. Kuznetsov, G. M. Mrevlishvili

Research output: Contribution to journal › Article › peer-review

Abstract

Statistical model of dsDNA packaging to icosahedral bacteriophage capsid is presented. The model describes intraphage DNA as a globule, i.e. intramolecular liquid crystal. We analyse the free energy of DNA, which has a globulized part inside the phage capsid and coil-like tail outside it. Conditions when processes of DNA movement into capsid or back are thermodynamically favorable are investigated. These processes are not accompanied with any thermal effects. It is not "all or none" type process, i.e. intermediate stable states are possible. The role of DNA interaction with the capsid inner wall is considered. The essential model abilities for qualitative explanation of experimental data are exhibited.

Translated title of the contribution	A theoretical model of DNA packaging in the phage head
Original language	Russian
Pages (from-to)	780-787
Number of pages	8
Journal	Biofizika
Volume	36
Issue number	5
State	Published - Sep 1991

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Teoreticheskaia model' upakovki DNK v golovke faga.",

abstract = "Statistical model of dsDNA packaging to icosahedral bacteriophage capsid is presented. The model describes intraphage DNA as a globule, i.e. intramolecular liquid crystal. We analyse the free energy of DNA, which has a globulized part inside the phage capsid and coil-like tail outside it. Conditions when processes of DNA movement into capsid or back are thermodynamically favorable are investigated. These processes are not accompanied with any thermal effects. It is not {"}all or none{"} type process, i.e. intermediate stable states are possible. The role of DNA interaction with the capsid inner wall is considered. The essential model abilities for qualitative explanation of experimental data are exhibited.",

author = "Gabashvili, {I. S.} and Grosberg, {A. I.} and Kuznetsov, {D. V.} and Mrevlishvili, {G. M.}",

year = "1991",

month = sep,

language = "Russian",

volume = "36",

pages = "780--787",

journal = "Biofizika",

issn = "0006-3029",

publisher = "Izdatel'stvo Nauka",

number = "5",

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TY - JOUR

T1 - Teoreticheskaia model' upakovki DNK v golovke faga.

AU - Gabashvili, I. S.

AU - Grosberg, A. I.

AU - Kuznetsov, D. V.

AU - Mrevlishvili, G. M.

PY - 1991/9

Y1 - 1991/9

N2 - Statistical model of dsDNA packaging to icosahedral bacteriophage capsid is presented. The model describes intraphage DNA as a globule, i.e. intramolecular liquid crystal. We analyse the free energy of DNA, which has a globulized part inside the phage capsid and coil-like tail outside it. Conditions when processes of DNA movement into capsid or back are thermodynamically favorable are investigated. These processes are not accompanied with any thermal effects. It is not "all or none" type process, i.e. intermediate stable states are possible. The role of DNA interaction with the capsid inner wall is considered. The essential model abilities for qualitative explanation of experimental data are exhibited.

AB - Statistical model of dsDNA packaging to icosahedral bacteriophage capsid is presented. The model describes intraphage DNA as a globule, i.e. intramolecular liquid crystal. We analyse the free energy of DNA, which has a globulized part inside the phage capsid and coil-like tail outside it. Conditions when processes of DNA movement into capsid or back are thermodynamically favorable are investigated. These processes are not accompanied with any thermal effects. It is not "all or none" type process, i.e. intermediate stable states are possible. The role of DNA interaction with the capsid inner wall is considered. The essential model abilities for qualitative explanation of experimental data are exhibited.

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M3 - Article

C2 - 1799593

AN - SCOPUS:0026217114

SN - 0006-3029

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JO - Biofizika

JF - Biofizika

IS - 5

ER -

Teoreticheskaia model' upakovki DNK v golovke faga.

Abstract

ASJC Scopus subject areas

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