A total synthesis prompts the structure revision of haouamine B

Maria Matveenko; Guangxin Liang; Erica M.W. Lauterwasser; Eva Zubía; Dirk Trauner

doi:10.1021/ja301326k

A total synthesis prompts the structure revision of haouamine B

Maria Matveenko, Guangxin Liang, Erica M.W. Lauterwasser, Eva Zubía, Dirk Trauner

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A concise asymmetric approach to the indeno-tetrahydropyridine core of the unusual alkaloid haouamine B allowed for an investigation of a biomimetic oxidative phenol coupling as a proposed biosynthetic step, and ultimately provided access to the published structure of the natural product. As a consequence of our synthetic studies, the structure of haouamine B has been revised.

Original language	English (US)
Pages (from-to)	9291-9295
Number of pages	5
Journal	Journal of the American Chemical Society
Volume	134
Issue number	22
DOIs	https://doi.org/10.1021/ja301326k
State	Published - Jun 6 2012

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja301326k

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abstract = "A concise asymmetric approach to the indeno-tetrahydropyridine core of the unusual alkaloid haouamine B allowed for an investigation of a biomimetic oxidative phenol coupling as a proposed biosynthetic step, and ultimately provided access to the published structure of the natural product. As a consequence of our synthetic studies, the structure of haouamine B has been revised.",

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AU - Trauner, Dirk

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A total synthesis prompts the structure revision of haouamine B

Abstract

ASJC Scopus subject areas

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