A Two-Stage Cascade Model with Variational Autoencoders and Attention Gates for MRI Brain Tumor Segmentation

Chenggang Lyu, Hai Shu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Automatic MRI brain tumor segmentation is of vital importance for the disease diagnosis, monitoring, and treatment planning. In this paper, we propose a two-stage encoder-decoder based model for brain tumor subregional segmentation. Variational autoencoder regularization is utilized in both stages to prevent the overfitting issue. The second-stage network adopts attention gates and is trained additionally using an expanded dataset formed by the first-stage outputs. On the BraTS 2020 validation dataset, the proposed method achieves the mean Dice score of 0.9041, 0.8350, and 0.7958, and Hausdorff distance (95%) of 4.953, 6.299, 23.608 for the whole tumor, tumor core, and enhancing tumor, respectively. The corresponding results on the BraTS 2020 testing dataset are 0.8729, 0.8357, and 0.8205 for Dice score, and 11.4288, 19.9690, and 15.6711 for Hausdorff distance. The code is publicly available at https://github.com/shu-hai/two-stage-VAE-Attention-gate-BraTS2020.

Original languageEnglish (US)
Title of host publicationBrainlesion
Subtitle of host publicationGlioma, Multiple Sclerosis, Stroke and Traumatic Brain Injuries - 6th International Workshop, BrainLes 2020, Held in Conjunction with MICCAI 2020, Revised Selected Papers
EditorsAlessandro Crimi, Spyridon Bakas
PublisherSpringer Science and Business Media Deutschland GmbH
Pages435-447
Number of pages13
ISBN (Print)9783030720834
DOIs
StatePublished - 2021
Event6th International MICCAI Brainlesion Workshop, BrainLes 2020 Held in Conjunction with 23rd Medical Image Computing for Computer Assisted Intervention Conference, MICCAI 2020 - Virtual, Online
Duration: Oct 4 2020Oct 4 2020

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12658 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference6th International MICCAI Brainlesion Workshop, BrainLes 2020 Held in Conjunction with 23rd Medical Image Computing for Computer Assisted Intervention Conference, MICCAI 2020
CityVirtual, Online
Period10/4/2010/4/20

Keywords

  • Attention gate
  • Brain tumor segmentation
  • Encoder-decoder network
  • Variational autoencoder

ASJC Scopus subject areas

  • Theoretical Computer Science
  • General Computer Science

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