A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene

Elodie Ghedin; Hugues Charest; Greg Matlashewski

doi:10.1016/S0166-6851(98)00027-9

A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene

Elodie Ghedin, Hugues Charest, Greg Matlashewski

Research output: Contribution to journal › Article › peer-review

Abstract

The A2-A2rel gene copies are arranged in tandem arrays on a 850 kb chromosome in Leishmania donovani. Contrary to A2 mRNA which displays amastigote-stage-specific expression, A2rel gene expression is constitutive throughout the L. donovani life cycle. The A2rel sequence was found to be conserved in all Leishmania species tested, while the A2 sequence is specific to L. donovani and L. mexicana.The A2rel full length cDNA is of 2.3 kb and it contains one open reading frame coding for a putative protein of 436 amino acids. Copyright (C) 1998 Elsevier Science B.V.

Original language	English (US)
Pages (from-to)	23-29
Number of pages	7
Journal	Molecular and Biochemical Parasitology
Volume	93
Issue number	1
DOIs	https://doi.org/10.1016/S0166-6851(98)00027-9
State	Published - May 15 1998

ASJC Scopus subject areas

Parasitology
Molecular Biology

Access to Document

10.1016/S0166-6851(98)00027-9

Cite this

@article{d303637d907148bdb1b570a2734f01b6,

title = "A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene",

abstract = "The A2-A2rel gene copies are arranged in tandem arrays on a 850 kb chromosome in Leishmania donovani. Contrary to A2 mRNA which displays amastigote-stage-specific expression, A2rel gene expression is constitutive throughout the L. donovani life cycle. The A2rel sequence was found to be conserved in all Leishmania species tested, while the A2 sequence is specific to L. donovani and L. mexicana.The A2rel full length cDNA is of 2.3 kb and it contains one open reading frame coding for a putative protein of 436 amino acids. Copyright (C) 1998 Elsevier Science B.V.",

author = "Elodie Ghedin and Hugues Charest and Greg Matlashewski",

note = "Funding Information: Research at the Institute of Parasitology is partially funded by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Fonds pour la formation de chercheurs et l'aide {\`a} la recherche du Qu{\'e}bec (FCAR). EG holds a PhD Studentship from FCAR and GM holds an MRC Scientist Award.",

year = "1998",

month = may,

day = "15",

doi = "10.1016/S0166-6851(98)00027-9",

language = "English (US)",

volume = "93",

pages = "23--29",

journal = "Molecular and Biochemical Parasitology",

issn = "0166-6851",

publisher = "Elsevier B.V.",

number = "1",

}

TY - JOUR

T1 - A2rel

T2 - a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene

AU - Ghedin, Elodie

AU - Charest, Hugues

AU - Matlashewski, Greg

N1 - Funding Information: Research at the Institute of Parasitology is partially funded by the Natural Sciences and Engineering Research Council of Canada (NSERC) and the Fonds pour la formation de chercheurs et l'aide à la recherche du Québec (FCAR). EG holds a PhD Studentship from FCAR and GM holds an MRC Scientist Award.

PY - 1998/5/15

Y1 - 1998/5/15

N2 - The A2-A2rel gene copies are arranged in tandem arrays on a 850 kb chromosome in Leishmania donovani. Contrary to A2 mRNA which displays amastigote-stage-specific expression, A2rel gene expression is constitutive throughout the L. donovani life cycle. The A2rel sequence was found to be conserved in all Leishmania species tested, while the A2 sequence is specific to L. donovani and L. mexicana.The A2rel full length cDNA is of 2.3 kb and it contains one open reading frame coding for a putative protein of 436 amino acids. Copyright (C) 1998 Elsevier Science B.V.

AB - The A2-A2rel gene copies are arranged in tandem arrays on a 850 kb chromosome in Leishmania donovani. Contrary to A2 mRNA which displays amastigote-stage-specific expression, A2rel gene expression is constitutive throughout the L. donovani life cycle. The A2rel sequence was found to be conserved in all Leishmania species tested, while the A2 sequence is specific to L. donovani and L. mexicana.The A2rel full length cDNA is of 2.3 kb and it contains one open reading frame coding for a putative protein of 436 amino acids. Copyright (C) 1998 Elsevier Science B.V.

UR - http://www.scopus.com/inward/record.url?scp=0042351392&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0042351392&partnerID=8YFLogxK

U2 - 10.1016/S0166-6851(98)00027-9

DO - 10.1016/S0166-6851(98)00027-9

M3 - Article

C2 - 9662025

AN - SCOPUS:0042351392

SN - 0166-6851

VL - 93

SP - 23

EP - 29

JO - Molecular and Biochemical Parasitology

JF - Molecular and Biochemical Parasitology

IS - 1

ER -

A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this