TY - JOUR
T1 - Ab initio protein structure prediction
T2 - Progress and prospects
AU - Bonneau, R.
AU - Baker, D.
PY - 2001
Y1 - 2001
N2 - Considerable recent progress has been made in the field of ab initio protein structure prediction, as witnessed by the third Critical Assessment of Structure Prediction (CASP3). In spite of this progress, much work remains, for the field has yet to produce consistently reliable ab initio structure prediction protocols. In this work, we review the features of current ab initio protocols in an attempt to highlight the foundations of recent progress in the field and suggest promising directions for future work.
AB - Considerable recent progress has been made in the field of ab initio protein structure prediction, as witnessed by the third Critical Assessment of Structure Prediction (CASP3). In spite of this progress, much work remains, for the field has yet to produce consistently reliable ab initio structure prediction protocols. In this work, we review the features of current ab initio protocols in an attempt to highlight the foundations of recent progress in the field and suggest promising directions for future work.
KW - Structural genomics, protein folding, scoring functions, fold prediction
UR - http://www.scopus.com/inward/record.url?scp=0034985005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034985005&partnerID=8YFLogxK
U2 - 10.1146/annurev.biophys.30.1.173
DO - 10.1146/annurev.biophys.30.1.173
M3 - Review article
C2 - 11340057
AN - SCOPUS:0034985005
SN - 1056-8700
VL - 30
SP - 173
EP - 189
JO - Annual Review of Biophysics and Biomolecular Structure
JF - Annual Review of Biophysics and Biomolecular Structure
ER -