(equation presented) A circular dichroism technique has been applied to the absolute configurational assignment of acyclic α-amino acids and β-amino alcohols with single stereogenic centers via a one-step derivitization procedure requiring microgram quantities of material. Metal ions fix the geometrical relationship of two chromophores, affording CD spectra that agree with theory on the basis of the expected conformation of the ligands in the metal complexes.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry