Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe; Sam Thompson; Andrew D. Hamilton

doi:10.1039/c6cc01496h

Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe, Sam Thompson, Andrew D. Hamilton

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

Original language	English (US)
Pages (from-to)	6521-6524
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	39
DOIs	https://doi.org/10.1039/c6cc01496h
State	Published - 2016

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c6cc01496h

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title = "Acid-mediated topological control in a functionalized foldamer",

abstract = "Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.",

author = "Knipe, {Peter C.} and Sam Thompson and Hamilton, {Andrew D.}",

note = "Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",

year = "2016",

doi = "10.1039/c6cc01496h",

language = "English (US)",

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AU - Knipe, Peter C.

AU - Thompson, Sam

AU - Hamilton, Andrew D.

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AB - Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

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JO - Chemical Communications

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Acid-mediated topological control in a functionalized foldamer

Abstract

ASJC Scopus subject areas

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