Actomyosin-dependent cortical dynamics

Patrizia Sommi, Dhanya Cheerambathur, Ingrid Brust-Mascher, Alex Mogilner

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The assembly of the Drosophila embryo mitotic spindle during prophase depends upon a balance of outward forces generated by cortical dynein and inward forces generated by kinesin-14 and nuclear elasticity. Myosin II is known to contribute to the dynamics of the cell cortex but how this influences the prophase force-balance is unclear.

Original languageEnglish (US)
Title of host publicationTrends in Biophysics
Subtitle of host publicationFrom Cell Dynamics Toward Multicellular Growth Phenomena
PublisherApple Academic Press
Pages49-69
Number of pages21
ISBN (Electronic)9781466584105
ISBN (Print)9781926895369
DOIs
StatePublished - Jan 1 2013

Keywords

  • Centrosomes
  • Drosophila
  • Myosin-II
  • Rhodamine-Actin
  • Spindle poles

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Physics and Astronomy

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