Actomyosin-dependent cortical dynamics

Patrizia Sommi, Dhanya Cheerambathur, Ingrid Brust-Mascher, Alex Mogilner

Research output: Chapter in Book/Report/Conference proceedingChapter


The assembly of the Drosophila embryo mitotic spindle during prophase depends upon a balance of outward forces generated by cortical dynein and inward forces generated by kinesin-14 and nuclear elasticity. Myosin II is known to contribute to the dynamics of the cell cortex but how this influences the prophase force-balance is unclear.

Original languageEnglish (US)
Title of host publicationTrends in Biophysics
Subtitle of host publicationFrom Cell Dynamics Toward Multicellular Growth Phenomena
PublisherApple Academic Press
Number of pages21
ISBN (Electronic)9781466584105
ISBN (Print)9781926895369
StatePublished - Jan 1 2013


  • Centrosomes
  • Drosophila
  • Myosin-II
  • Rhodamine-Actin
  • Spindle poles

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Physics and Astronomy


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