TY - GEN
T1 - ADHESIVE BANDAGE FOR SARS-CoV-2 IMMUNE RESPONSE DETECTION AND SCREENING
AU - Boumar, Imen
AU - Deliorman, Muhammedin
AU - Qasaimeh, Mohammad A.
N1 - Publisher Copyright:
© 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
PY - 2021
Y1 - 2021
N2 - In this work, we report the initial development steps of a finger stick point-of-care device (adhesive bandage) for timely detection/screening of immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The bandage, comprising vertically stacked serum separation membrane, conjugate pad, and detection (readout) zone, aims to colloid-capture SARS-CoV-2-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies from a pinprick (~10 µL) of blood in one step, and visually display results in forms of no immune IgM-/IgG-, early immune IgM+/IgG-, active immune IgM+/IgG+, and immune IgM-/IgG+ in short time (minutes).
AB - In this work, we report the initial development steps of a finger stick point-of-care device (adhesive bandage) for timely detection/screening of immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The bandage, comprising vertically stacked serum separation membrane, conjugate pad, and detection (readout) zone, aims to colloid-capture SARS-CoV-2-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies from a pinprick (~10 µL) of blood in one step, and visually display results in forms of no immune IgM-/IgG-, early immune IgM+/IgG-, active immune IgM+/IgG+, and immune IgM-/IgG+ in short time (minutes).
KW - Adhesive bandage
KW - Colloid-capture
KW - Hybrid flow assay
KW - IgG
KW - IgM
KW - SARS-CoV-2
KW - Screening
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M3 - Conference contribution
AN - SCOPUS:85136960251
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 851
EP - 852
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Y2 - 10 October 2021 through 14 October 2021
ER -