TY - JOUR
T1 - Alterations in purine salvage and hypoxanthine levels in granulation tissue during skin wound repair
AU - Rossomando, Edward F.
AU - Bertolami, Charles N.
N1 - Funding Information:
1 Supported in part by grants from the National Institutes of Health, DE 04657 and DE 03715 (E.F.R.) and University of Connecticut Research Foundation (C.N.B.) 2 Reprint requests should be sent to Edward F. Ros-somando, D.D.S./Ph.D., Department of Oral Biology, School of Dental Medicine, University of Connecticut Health Center, Farmington, Conn. 06032.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1983/9
Y1 - 1983/9
N2 - We report the levels of hypoxanthine in rabbit skin granulation tissue, harvested at different postwound intervals and from various locations within the wounds. The effect of full-thickness autogenous skin grafts on hypoxanthine levels has also been examined. The levels of inosine, xanthine, adenosine 5′-monophosphate, and inosine 5′-monophosphate are reported as well. The correlation between the level of these compounds and the healing process suggests they may be useful indicators of the extent of tissue damage.
AB - We report the levels of hypoxanthine in rabbit skin granulation tissue, harvested at different postwound intervals and from various locations within the wounds. The effect of full-thickness autogenous skin grafts on hypoxanthine levels has also been examined. The levels of inosine, xanthine, adenosine 5′-monophosphate, and inosine 5′-monophosphate are reported as well. The correlation between the level of these compounds and the healing process suggests they may be useful indicators of the extent of tissue damage.
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U2 - 10.1016/S0022-4804(83)80012-2
DO - 10.1016/S0022-4804(83)80012-2
M3 - Article
C2 - 6350711
AN - SCOPUS:0020506549
SN - 0022-4804
VL - 35
SP - 259
EP - 263
JO - Journal of Surgical Research
JF - Journal of Surgical Research
IS - 3
ER -