Amelioration of the premature ageing-like features of Fgf-23 knockout mice by genetically restoring the systemic actions of FGF-23

Keyphrases

• Systemic Action 100%
• Fibroblast Growth Factor 23 (FGF23) 100%
• Premature Aging 100%
• Abnormal Phenotype 5%
• Soft Tissue Calcification 5%
• Hyperphosphataemia 5%
• Renal Expression 5%
• Ion Metabolism 5%
• Hypophosphataemia 5%
• Phosphate Homeostasis 5%
• Kyphosis 5%
• Vitamin D Metabolism 5%
• CYP27B1 5%
• Prolonged Survival 5%
• Tg Mouse 5%
• Pulmonary Emphysema 5%
• Hypervitaminosis D 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Fibroblast Growth Factor 23 100%
• Premature Aging 100%
• Hypervitaminosis D 11%
• Soft Tissue Calcification 11%
• Hyperphosphatemia 11%
• Hypogonadism 11%
• Lung Emphysema 11%
• Kyphosis 11%

Biochemistry, Genetics and Molecular Biology

• Fibroblast Growth Factor 23 100%
• Vitamin D Metabolism 11%
• Hypervitaminosis D 11%