Abstract
The first cis,cis,cis,trans-[5.5.5.5]-fenestranes have been synthesized in three steps using a novel arene-alkene photocycloaddition-radical cyclization cascade, which creates overall 5 new rings and 8 stereogenic centers. A lead tetraacetate mediated ring expansion of a 5,5-fused ring system, discovered in the course of exploring the chemistry of these new materials, is also described.
Original language | English (US) |
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Pages (from-to) | 7687-7690 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 37 |
Issue number | 43 |
DOIs | |
State | Published - Oct 21 1996 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry