An evaluation of anti-oxidative protection for cells against atmospheric pressure cold plasma treatment

Ruonan Ma, Hongqing Feng, Fangting Li, Yongdong Liang, Qian Zhang, Weidong Zhu, Jue Zhang, Kurt H. Becker, Jing Fang

Research output: Contribution to journalArticlepeer-review

Abstract

With the development of plasma medicine, safety issues are emerging as a serious concern. In this study, both intracellular (genetic engineering) and extracellular (scavengers) measures were tested in an effort to determine the best protection for cells against plasma-induced oxidative stress. All results of immediate reactive species detection, short term survival and long term proliferation, suggest that intracellular pathways are superior in reducing oxidative stress and cell death. This work provides a potential mechanism to enhance safety and identifies precautionary measures that should be taken in future clinical applications of plasmas.

Original languageEnglish (US)
Article number123701
JournalApplied Physics Letters
Volume100
Issue number12
DOIs
StatePublished - Mar 19 2012

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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