We present an analytical method for determining the designability of protein structures. We apply our method to the case of two-dimensional lattice structures, and give a systematic solution for the spectrum of any structure. Using this spectrum, the designability of a structure can be estimated. We outline a hierarchy of structures, from most to least designable, and show that this hierarchy depends on the potential that is used.
ASJC Scopus subject areas
- Physics and Astronomy(all)