Annexins - their role in cartilage mineralization.

Thorsten Kirsch

Research output: Contribution to journalReview articlepeer-review


Annexins II, V and VI are highly expressed by hypertrophic and terminally differentiated growth plate chondrocytes and by osteoblasts. Because of the localization of annexins in areas of cartilage and bone mineralization, we hypothesized that these annexins play a regulatory role in the mineralization process. In this article we review the function of annexins II, V and VI in physiological mineralization of skeletal tissues and in pathological mineralization of articular cartilage.

Original languageEnglish (US)
Pages (from-to)576-581
Number of pages6
JournalFrontiers in bioscience : a journal and virtual library
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology


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