TY - JOUR
T1 - Antigen processing and presentation of vesicular stomatitis virus glycoprotein
AU - Reiss, C. S.
PY - 1993
Y1 - 1993
N2 - Antigen processing and presentation is the complex series of steps involving numerous compartments of cells derived from multiple lineages. This collective process is central to the initiation of specific cellular immune responses. Internalization of foreign proteins or infectious agents, degradation of proteins to peptides, and transfer to 1a heterodimers which are then translocated to the cell surface, comprise the pathway. This can be blocked by drugs which interfere with compartment acidification (ammonium chloride, methylamine, chloroquine), protein synthesis (emetine), vesicle trafficking (brefeldin A), and microtubule metabolism (taxol, colchicine, nocadazole).
AB - Antigen processing and presentation is the complex series of steps involving numerous compartments of cells derived from multiple lineages. This collective process is central to the initiation of specific cellular immune responses. Internalization of foreign proteins or infectious agents, degradation of proteins to peptides, and transfer to 1a heterodimers which are then translocated to the cell surface, comprise the pathway. This can be blocked by drugs which interfere with compartment acidification (ammonium chloride, methylamine, chloroquine), protein synthesis (emetine), vesicle trafficking (brefeldin A), and microtubule metabolism (taxol, colchicine, nocadazole).
KW - Antigen presentation
KW - Antigen processing
KW - Endosome
KW - Ia biosynthesis
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U2 - 10.1006/smvy.1993.1004
DO - 10.1006/smvy.1993.1004
M3 - Article
AN - SCOPUS:43949169637
VL - 4
SP - 101
EP - 107
JO - Advances in Virus Research
JF - Advances in Virus Research
SN - 0065-3527
IS - 2
ER -