Antihypertensive medication compliance: A comparison between Brazilian men and women

Ana Carolina Queiroz Godoy Daniel, Juliana Pereira Machado, Claudia Benedita dos Santos, Miyeko Hayashida, Paloma César de Sales, Simone Maria Muniz da Silva Bezzera, Deborah Chyun, Eugenia Velludo Veiga

Research output: Contribution to journalArticlepeer-review


Background: Hypertension is a major cause of morbidity and mortality worldwide. Medication compliance is a challenge for patients and health professionals. The aim of this work was to compare the degree of antihypertensive medication compliance between Brazilian men and women.

Methods: From March to May 2009, we conducted a non-experimental, comparative study, which analysed a sample of 80 patients diagnosed with HTN who were undergoing medical treatment and had been admitted to a hospital in the state of São Paulo.

Results: Most patients in the sample were women (66.2%), white (81.2%), married (55%), and with a lower educational level (80%). Their mean age was 62 years (SD= 14.1). Approximately forty-nine percent (49.1%) of the women and thirty-seven percent (37%) of the men from the sample complied with the treatment (p=0.307), however differences were observed in the individual compliance-related behaviours.

Conclusions: Although this study did not show a statistically significant association between genders in relation to medication compliance, gender differences in compliance-related behaviours deserves attention. Therefore, we suggest that additional studies focusing on gender-difference be conducted so that individualized interventions can be developed.

Original languageEnglish (US)
Article number1000328
JournalJournal of Clinical and Experimental Cardiology
Issue number8
StatePublished - 2014


  • Drug effects
  • Hypertension
  • Hypertension pharmacology
  • Hypertension therapy
  • Patient compliance
  • Patient compliance

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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