Arsenic exposure from drinking-water and carotid atery intima-medial thickness in healthy young adults in Bangladesh

Yu Chen, Mohammed Enamul Hakim, Faruque Parvez, Tariqul Islam, Atiar M. Rahman, Habibul Ahsan

Research output: Contribution to journalArticlepeer-review

Abstract

Epidemiological studies have linked high levels (>200 μg/L) of chronic exposure to arsenic in drinking-water with elevated risks of several vascular diseases. In this pilot study, the association between low-level arsenic exposure and carotid artery intimal-medial thickness (IMT) was evaluated among 66 healthy, normotensive, relatively young individuals (mean age 35 years) participating in the ongoing Health Effects of Arsenic Longitudinal Study in Bangladesh. Participants with a higher carotid IMT (>0.75 mm) in general had higher levels of past chronic exposure of arsenic than those with a lower carotid IMT (≤0.75 mm). Although the differences in average arsenic exposure between the two groups were not statistically significant, the findings suggest a possible association between low-level arsenic exposure from drinking-water and carotid atherosclerosis, warranting the need for larger studies.

Original languageEnglish (US)
Pages (from-to)253-257
Number of pages5
JournalJournal of Health, Population and Nutrition
Volume24
Issue number2
StatePublished - Jun 2006

Keywords

  • Arsenic
  • Arsenic exposure
  • Atherosclerosis
  • Bangladesh
  • Carotid arteries
  • Drinking-water

ASJC Scopus subject areas

  • Food Science
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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