Arsenic exposure in children

Antonio J. Signes-Pastor, Fen Wu, Shohreh F. Farzan, Yu Chen, Margaret R. Karagas

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Arsenic is a human carcinogen and neurotoxicant. Consumption of arsenic-contaminated groundwater is a major source of human exposure worldwide. Groundwater contamination, most of it from natural sources, has been reported in regions of South Asia and Taiwan as well as South and North America among others. Exposure commonly occurs through diet, including rice and rice products fed to babies and young children. Chronic exposure to inorganic arsenic in early development, especially exposure in utero, is associated with neurodevelopmental, respiratory, cardiovascular reproductive, and long-term cancer outcomes. Prevention of exposure to arsenic in well water can be achieved via comprehensive well testing, promotion of switching to uncontaminated wells, provision of filtration devices, and utilization of deeper aquifers that are low in arsenic. Agricultural and food processing practices along with dietary choices can limit arsenic exposure via diet. Such interventions combined with policy and practice actions are urgently needed to protect children lifelong.

Original languageEnglish (US)
Title of host publicationTextbook of Children's Environmental Health
Subtitle of host publicationSecond Edition
PublisherOxford University Press
Pages437-450
Number of pages14
ISBN (Electronic)9780197662564
ISBN (Print)9780197662526
DOIs
StatePublished - Jul 18 2024

Keywords

  • Arsenic
  • Bangladesh
  • Bronchiectasis
  • Cancer
  • Drinking water
  • Mitigation
  • Neurotoxicity
  • Pulmonary effects
  • Reproductive
  • Toxicology

ASJC Scopus subject areas

  • General Medicine

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