Assessment and Management of Cancer- and Cancer Treatment–Related Cognitive Impairment

Cognitive impairment resulting from cancer and subsequent treatment is one of the most common and troubling sequelae experienced by cancer survivors. Cancer survivors report that cognitive impairment negatively affects their quality of life. Appropriate assessment and management of cognitive impairment is critical to providing optimal care to cancer survivors. The purpose of this article is to briefly describe the state of evidence on incidence, possible mechanisms, and presentation of cancer- and cancer treatment–related cognitive impairment and to provide guidance for its assessment and management. We focus on management with nonpharmacological and pharmacological interventions that may have clinical utility.